1547-91-7Relevant academic research and scientific papers
IMIDAZO [1,2-A] PYRIDINE COMPOUNDS
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Page/Page column 96, (2009/08/14)
This invention relates generally to imidazo [1,2-a] pyridine-based modulators of Liver X receptors (LXRs) and related methods.
NOVEL COMPOUNDS
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Page/Page column 24, (2008/06/13)
The present invention relates to novel indole derivatives such as compounds of the formula (I): which possess antagonist potency at the 5-HT6 receptor and the use of such compounds or pharmaceutically acceptable salts or solvates thereof in the treatment of Alzheimer's disease and other CNS disorders.
General and Highly Efficient Syntheses of m-Fluoro Arenes Using Potassium Fluoride-Exchange Method
Suzuki, Hiroshi,Yazawa, Naoto,Yoshida, Yasuo,Furusawa, Osamu,Kimura, Yoshikazu
, p. 2010 - 2017 (2007/10/02)
Tetraphenylphosphonium bromide was found to be a suitable catalyst for the reaction of m-nitroaryl derivatives carrying cyano, nitro, chlorocarbonyl, trifluoromethyl, and chlorosulfonyl groups with potassium fluoride in the presence of a stoichiometric amount of phthaloyl dichloride, giving the corresponding m-fluoro aromatic derivatives in good yields.The catalyst was also found to be efficient for the fluorodesulfonylation of m-(fluorosulfonyl)aryl derivatives to afford m-fluoro arenes by the use of a reaction-distillation technique.
Tetraphenylphosphonium Bromide Catalyzed Fluorodenitrations and Fluorodesulfonylations. Efficient Syntheses of m-Fluoroaromatic Compounds
Yazawa, Naoto,Suzuki, Hiroshi,Yoshida, Yasuo,Furusawa, Osamu,Kimura, Yoshikazu
, p. 2213 - 2216 (2007/10/02)
Meta-fluoroaromatic compounds were effectively synthesized from m-nitroaromatic or m-fluorosulfonylaromatic compounds by replacement reaction with potassium fluoride in the presence of a catalytic amount of tetraphenylphosphonium bromide.
