154715-77-2

Basic information

• Product Name: Benzoic acid, 2,5-dihydroxy-, 1,1-diMethylethyl ester
• Synonyms: Benzoic acid, 2,5-dihydroxy-, 1,1-diMethylethyl ester
• CAS NO: 154715-77-2
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 210.22646
• EINECS: -0
• Mol File: 154715-77-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 2,5-dihydroxy-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,5-dihydroxy-, 1,1-diMethylethyl ester(154715-77-2)
• EPA Substance Registry System: Benzoic acid, 2,5-dihydroxy-, 1,1-diMethylethyl ester(154715-77-2)

Safety Data

• Hazardous Substances Data: 154715-77-2(Hazardous Substances Data)

Upstream product

• 490-79-9 2,5-dihydroxybenzoic acid. 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 1071817-59-8 tert-butyl 2,5-bis(methoxymethoxy)benzoate 

Relevant articles and documents

A route to 1,4-disubstituted aromatics and its application to the synthesis of the antibiotic culpin

(Chemical Equation Presented) A method is described for converting tert-butyl benzoates or tert-butyl 1-naphthoates into derivatives having an alkyl or substituted alkyl group in a 1,4-relationship to an alkyl, aryl, alkenyl, or alkynyl group. Key steps in the sequence are (i) addition of an organometallic species to a cross-conjugated cyclohexadienone obtained by Birch alkylation of a tert-butyl benzoate or a tert-butyl 1-naphthoate, followed by allylic oxidation, and (ii) treatment with BiCl3·H 2O, which results in removal of the tert-butyl group and spontaneous decarboxylative aromatization. The method was applied to the synthesis of the antimicrobial fungal metabolite culpin.