154738-03-1

Basic information

• Product Name: 3',5'-O-[bis-(tert-butyldimethylsilyl)]-4-N-(triphenylmethylsulfenyl)deoxycytidine
• Synonyms: 3',5'-O-[bis-(tert-butyldimethylsilyl)]-4-N-(triphenylmethylsulfenyl)deoxycytidine
• CAS NO: 154738-03-1
• Molecular Weight: 730.131
• Mol File: 154738-03-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3',5'-O-[bis-(tert-butyldimethylsilyl)]-4-N-(triphenylmethylsulfenyl)deoxycytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-O-[bis-(tert-butyldimethylsilyl)]-4-N-(triphenylmethylsulfenyl)deoxycytidine(154738-03-1)
• EPA Substance Registry System: 3',5'-O-[bis-(tert-butyldimethylsilyl)]-4-N-(triphenylmethylsulfenyl)deoxycytidine(154738-03-1)

Safety Data

• Hazardous Substances Data: 154738-03-1(Hazardous Substances Data)

Upstream product

• 51549-29-2 2'-deoxy-3',5'-bis-O-(tert-butyldimethylsilyl)cytidine 
• 205238-86-4 1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-4-(2-nitro-phenylsulfanylamino)-1H-pyrimidin-2-one 
• 24165-03-5 tritylsulfenyl chloride 

Downstream Products

• 205238-92-2 N-{1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-N-(2-nitro-phenylsulfanyl)-acetamide 
• 205238-86-4 1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-4-(2-nitro-phenylsulfanylamino)-1H-pyrimidin-2-one 

Relevant articles and documents

A reinvestigation of sulfenyl groups as amino protecting groups for the synthesis of oligonucleotides on solid support by phosphoramidite chemistry

Although sulfenyl groups as protectors of heterocyclic amines of nucleosides appeared satisfactory during the synthesis of DNA and RNA via the phosphotriester approach, their usefulness in automated synthesis of oligonucleotides using phosphoramidite chem