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154742-09-3

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154742-09-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 154742-09-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,7,4 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 154742-09:
(8*1)+(7*5)+(6*4)+(5*7)+(4*4)+(3*2)+(2*0)+(1*9)=133
133 % 10 = 3
So 154742-09-3 is a valid CAS Registry Number.

154742-09-3Relevant articles and documents

Improving the Affinity and Selectivity of a Nonpeptide Series of Cholecystokinin-B/Gastrin Receptor Antagonists Based on the Dibenzobicyclooctane Skeleton

Kalindjian, S. Barret,Buck, Ildiko M.,Cushnir, Julia R.,Dunstone, David J.,Hudson, Martin L.,et al.

, p. 4294 - 4302 (2007/10/03)

We have recently described a novel series of nonpeptidic cholecystokinin-B (CCKB)/gastrin receptor antagonists based on a dibenzobicyclooctane skeleton.We wish now to report on compounds arising out of our earlier work which have substantially greater affinity as antagonists for the CCKB/gastrin receptor system and which maintain, or improve on, the already high selectivity with respect to CCKA receptors.Thus, cis-7-carbonyl>-2-phenylethyl>amino>carbonyl>-8--carbonyl>-2,3:5,6-dibenzobicycloi of 8.80 in mouse cortical membranes at CCKB/gastrin receptors.THe selectivity for these receptors over CCKA receptors was in the order of 1000-fold.

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