1547432-67-6

Upstream product

• 536-74-3 phenylacetylene 
• 14476-62-1 1-Ethylthio-2-phenyl-acetylen 
• 23652-91-7 (Z)-1-methyl-1-(N-acetyl)amino-2-acetylethylene 
• 103-82-2 phenylacetic acid 
• 123-54-6 acetylacetone 
• 1118-66-7 4-Aminopent-3-en-2-one 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 107622-90-2 4,6-dimethyl-3-phenylpyridin-2(1H)-one 
• 1547432-33-6 4,6-dimethyl-3-phenylpyridin-2-yl nonaflate 
• 52987-19-6 2-benzyl-6-methyl-4-phenylpyridine 
• 1547432-27-8 2-benzyl-6-methylpyridin-4-yl nonaflate 
• 109810-16-4 2,6-dimethyl-3,4-diphenylpyridine 

Relevant academic research and scientific papers

Zinc-catalyzed reaction of isoxazoles with thioynol ethers involving an unprecedented 1,2-sulfur migration

A novel zinc-catalyzed reaction of isoxazoles with thioynol ethers involving an unprecedented 1,2-sulfur migration has been developed, which represents the first example of a non-noble metal-catalyzed reaction between isoxazoles and alkynes. This method a

Trimethylsilyl trifluoromethanesulfonate-promoted cyclocondensation of β-ketoenamides and subsequent nonaflation to pyrid-2-yl and pyrid-4-yl nonaflates as flexible precursors for polysubstituted pyridines

The intramolecular condensation of β-ketoenamides to 2- and/or 4-pyridone derivatives using either KOt-Bu or trimethylsilyl trifluoromethanesulfonate/Hu?nig's base was investigated. Subsequent nonaflation of the cyclization products allowed a facile purification and further functionalization through Suzuki-Miyaura couplings leading to new highly substituted pyridine derivatives. The dependence of the regioselectivity of cyclocondensation on the structure of the β-ketoenamides is discussed. Georg Thieme Verlag Stuttgart New York.