15475-13-5

Basic information

• Product Name: 3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolane-2-carboxylic acid
• Synonyms: 3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolane-2-carboxylic acid
• CAS NO: 15475-13-5
• Molecular Formula: C₁₀H₁₀N₄O₆
• Molecular Weight: 282.21
• Mol File: 15475-13-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 820.6°Cat760mmHg
• Flash Point: 450.1°C
• Appearance: /
• Density: 2.24g/cm³
• Vapor Pressure: 1.71E-28mmHg at 25°C
• Refractive Index: 1.925
• CAS DataBase Reference: 3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolane-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolane-2-carboxylic acid(15475-13-5)
• EPA Substance Registry System: 3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolane-2-carboxylic acid(15475-13-5)

Safety Data

• Hazardous Substances Data: 15475-13-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10N4O6/c15-4-5(16)9(20-6(4)10(18)19)14-2-13-3-7(14)11-1-12-8(3)17/h1-2,4-6,9,15-16H,(H,18,19)(H,11,12,17)

Upstream product

• 28440-13-3 (3aS,4S,6R,6aR)-2,2-dimethyl-6-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuro[3,4-d][1,3]dioxole-4-carboxylic acid 
• 118101-43-2 inosine-5'-aldehyde 
• 58-63-9 Inosine 
• 58-63-9 inosine 
• 2140-11-6 2',3'-O-isopropylideneinosine 

Downstream Products

• 75930-32-4 N-<2-(3-cyclohexylureido)ethyl>-1-deoxy-1-(1,6-dihydro-6-oxo-9H-purin-9-yl)-β-D-ribofuranuronamide 
• 75930-30-2 1-deoxy-1-(1,6-dihydro-6-oxo-9H-purin-9-yl)-N-<2-(3-methylureido)ethyl>β-D-ribofuranuronamide 
• 68-94-0 Allopurinol 
• 58-63-9 Inosine 
• 75930-23-3 1-deoxy-1-(1,6-dihydro-6-oxo-9H-purin-9-yl)-N-<2-(3-methyl-3-nitrosoureido)ethyl>β-D-ribofuranuronamide 
• 75930-25-5 N-<2-(3-cyclohexyl-1-nitrosoureido)ethyl>-1-deoxy-1-(1,6-dihydro-6-oxo-9H-purin-9-yl)-β-D-ribofuranuronamide 

Relevant articles and documents

A versatile procedure for the generation of nucleoside 5'- carboxylic acids using nucleoside oxidase

The nucleoside oxidase from Stenotrophomonas maltophilia (FERM BP-2252) has been used to generate 5'-carboxylic acid derivatives of nucleoside analogues. The enzyme, which has a surprisingly broad substrate specificity for unnatural nucleosides, has been

Purification and Reaction of a New Enzyme, Nucleoside Oxidase

Nucleoside oxidase, a novel nucleoside oxidizing enzyme has been purified from a crude extract of Pseudomonas maltophilia LB-86 by a ammonium sulfate fractination, heat treatment, column chomatography on DEAE-Toyopearl, and gel filtration twice on Sephacryl S-200.The overall purification was approximately 60-fold with a yield of 35 percent.The purified enzyme gave a single protein band on acrylamide gel electrophoresis.Reaction products from inosine were identified as inosine-5'-aldehyde and inosine-5'-carboxylic acid.The enzyme catalyzed the oxidation of inosine to inosine-5'-carboxylic acid via inosine-5'-aldehyde using molecular oxygen as a primary electron acceptor with no formation of hydrogen peroxide.