A versatile procedure for the generation of nucleoside 5'- carboxylic acids using nucleoside oxidase

DOI: 10.1016/S0040-4020(98)00456-6

Source and publish data:

Tetrahedron p. 8171 - 8182 (1998)

Update date:2022-08-31

Topics:

Authors:

Mahmoudian, Mahmoud

Rudd, Brian A.M.

Cox, Brian

Drake, Chris S.

Hall, Richard M.

Stead, Paul

Dawson, Michael J.

Chandler, Malcolm

Livermore, David G.

Turner, Nicholas J.

Jenkins, Gareth

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Article abstract of DOI:10.1016/S0040-4020(98)00456-6

The nucleoside oxidase from Stenotrophomonas maltophilia (FERM BP-2252) has been used to generate 5'-carboxylic acid derivatives of nucleoside analogues. The enzyme, which has a surprisingly broad substrate specificity for unnatural nucleosides, has been

Full text of DOI:10.1016/S0040-4020(98)00456-6

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