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Methotrexate sodium is a synthetic antimetabolite medication that is primarily used to treat cancer, arthritis, and certain autoimmune conditions. It functions by inhibiting the growth of cancer cells and suppressing the immune system. Methotrexate sodium interferes with the production of DNA and RNA in cancer cells, leading to their death. It also helps reduce inflammation and swelling in the joints, making it effective for arthritis and autoimmune conditions. Due to its potential for serious side effects, such as liver damage and suppression of bone marrow function, Methotrexate sodium should be used with caution and under regular monitoring by a healthcare professional.

15475-56-6

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15475-56-6 Usage

Uses

Used in Oncology:
Methotrexate sodium is used as an anticancer agent for the treatment of various types of cancer. It is particularly effective against solid tumors and works by inhibiting the synthesis of DNA and RNA in cancer cells, ultimately leading to their death.
Used in Rheumatology:
Methotrexate sodium is used as a disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis and other inflammatory joint diseases. It helps to reduce inflammation and swelling in the joints, providing relief from pain and improving joint function.
Used in Autoimmune Conditions:
Methotrexate sodium is used as an immunosuppressive agent for the treatment of certain autoimmune conditions, such as psoriasis, lupus, and vasculitis. It suppresses the immune system, reducing inflammation and preventing the progression of these conditions.
Used in Pharmaceutical Industry:
Methotrexate sodium is used as a key ingredient in various pharmaceutical formulations for the treatment of cancer, arthritis, and autoimmune conditions. It is available in different forms, such as tablets, injections, and oral solutions, to cater to the specific needs of patients.

Check Digit Verification of cas no

The CAS Registry Mumber 15475-56-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,7 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15475-56:
(7*1)+(6*5)+(5*4)+(4*7)+(3*5)+(2*5)+(1*6)=116
116 % 10 = 6
So 15475-56-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H22N8O5.2Na/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);;/q;2*+1/p-2/t13-;;/m0../s1

15475-56-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Methotrexate sodium

1.2 Other means of identification

Product number -
Other names Einecs 239-495-5

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15475-56-6 SDS

15475-56-6Upstream product

15475-56-6Relevant academic research and scientific papers

Methotrexate compositions

-

Page/Page column 8-9, (2008/06/13)

A powder containing methotrexate particles in liquid crystal form suitable for inhalation.

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