154774-23-9Relevant academic research and scientific papers
Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity
Zheng, Shaojun,Laraia, Luca,O'Connor, Cornelius J.,Sorrell, David,Tan, Yaw Sing,Xu, Zhaochao,Venkitaraman, Ashok R.,Wu, Wenjun,Spring, David R.
, p. 2590 - 2593 (2012)
A novel synthesis of the ellagitannin natural product tellimagrandin I and a series of medium ring analogues is described. These compounds were all subsequently screened for redox activity, ability to precipitate protein and cellular phenotype in HeLa cel
Ellagitannin chemistry. The first total chemical synthesis of an ellagitannin natural product, tellimagrandin I
Feldman, Ken S.,Ensel, Susan M.,Minard, Robert D.
, p. 1742 - 1745 (2007/10/02)
Tellimagrandin I was synthesized by two different biogenetically patterned routes. One route featured diastereoselective galloyl ester coupling between the O(4) and O(6) galloyl moieties in a glucose-derived substrate bearing additional protected galloyl
