154808-40-9

Upstream product

• 154808-39-6 (1S,2S,3S)-(+)-1-cyclohexyl-2,3-epoxy-3-(trimethylsilyl)-1-propanol 
• 133216-88-3 (+/-)-1-cyclohexyl-3-(trimethylsilyl)-2-propynol 
• 112497-26-4 (E)-(+/-)-1-cyclohexyl-3-(trimethylsilyl)-2-propenol 
• 1066-54-2 trimethylsilylacetylene 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 154808-41-0 (1R,2S,3S)-(-)-1-cyclohexyl-2,3-epoxy-1-(4-fluorophenyl)-3-(trimethylsilyl)-1-propanol 
• 154808-45-4 (R)-(-)-3-cyclohexyl-3-(4-fluorophenyl)-3-hydroxypropyl toluenesulfonate 
• 154808-42-1 (4R,5S)-(-)-4-cyclohexyl-4-(4-fluorophenyl)-5-(trimethylsilyl)methyl-1,3-dioxolan-2-one 
• 154808-51-2 (1R,2S)-(+)-1-cyclohexyl-1-(4-fluorophenyl)-3-(trimethylsilyl)propane-1,2-diol 
• 154808-43-2 (R)-(-)-1-cyclohexyl-1-(4-fluorophenyl)-2-propenol 

Relevant academic research and scientific papers

Anticholinergic agents. 4. Stereocontrolled synthesis of fluorinated acetylcholine antagonists; syntheses of the two 1-cyclohexyl-1-(4-fluorophenyl)-3-piperidyl-1-propanols and their methiodides.

Four new putative muscarinic antagonists, (R)-(-)- and (S)-(+)-1-cyclohexyl-1-(4-fluorophenyl)-3-piperidyl-1-propanol and their methiodides, have been synthesised. Absolute configurations have been assigned on the basis of the anticipated chirality of the