154812-13-2

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 103-49-1 dibenzylamine 
• 119153-87-6 (C₅H₉O₂)C₉H₉NO(O)(CO₂C₂H₅) 

Downstream Products

• 1040485-06-0 (2S)-2-amino-N,N-bis(phenylmethyl)benzenepropanamide 
• 1040485-11-7 (2S)-2-amino-3-phenylmethyl-1-[bis(phenylmethyl)amino]propane 
• 1269764-46-6 (S)-N-(1-(dibenzylamino)-3-phenylpropan-2-yl)-4-methylbenzamide 
• 1269764-47-7 (S)-N-(1-amino-3-phenylpropan-2-yl)-4-methylbenzamide 
• 1269764-48-8 (S)-tert-butyl 2-((S)-2-(4-methylbenzamido)-3 phenylpropylcarbamoyl)pyrrolidine-1-carboxylate 
• 1269764-43-3 (S)-N-((S)-2-(4-methylbenzamido)-3-phenylpropyl)pyrrolidine-2-carboxamide 

Relevant academic research and scientific papers

REDOX DEHYDRATION COUPLING CATALYSTS AND METHODS RELATED THERETO

This disclosure relates to synthetic coupling methods using catalytic molecules. In certain embodiments, the catalytic molecules comprise heterocyclic thiolamide, S-acylthiosalicylamide, disulfide, selenium containing heterocycle, diselenide compound, ditelluride compound or tellurium containing heterocycle. Catalytic molecules disclosed herein are useful as catalysts in the transformation of hydroxy group containing compounds to amides, esters, ketones, and other carbon to heteroatom or carbon to carbon transformations.

Highly diastereo- and enantioselective direct Barbas-List aldol reactions promoted by novel benzamidoethyl and benzamidopropyl prolinamides in water

Four novel benzamido-functionalized prolinamides have been prepared and tested as organocatalysts for enantioselective aldol reaction of aldehydes and cyclic ketones in water. In particular, prolinamide derived from achiral ethylene diamine was the best c

Highly enantio- and diastereoselective synthesis of α- trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst

The first enantioselective Michael addition of α-cyanoketones to α,β-unsaturated trifluoromethyl ketones using a novel piperazine-thiourea catalyst was described. The resulting α- trifluoromethyldihydropyrans were obtained in high yields and with up to 95

Stereoselective synthesis of a novel chiral piperazine

(2S,6S)-2,4,6-Tris(phenylmethyl)piperazine was prepared in 11 steps and 53% overall yield from S-phenylalanine. Key steps in the synthesis involved reductive amination to introduce an ethoxycarbonylmethyl group on to the secondary nitrogen of the product