15482-67-4

Upstream product

• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 22362-66-9 3,5-dibromo-2-hydroxyacetophenone 
• 100-52-7 benzaldehyde 
• 118-93-4 o-hydroxyacetophenone 
• 888-12-0 (E)-2'-hydroxy-chalcone 

Downstream Products

• 42079-80-1 6,8-dibromo-2-phenyl-chroman-4-one 
• 42079-81-2 6,8-dibromo-2-phenyl-4H-chromen-4-one 
• 10372-55-1 3',5'-dibromo-2'-hydroxychalcone dibromide 

Relevant academic research and scientific papers

Site-Selective Suzuki-Miyaura Reaction of 6,8-Dibromoflavone

8-Aryl- and 6,8-diarylflavones were prepared by Suzuki-Miyaura reactions of 6,8-dibromoflavone. In spite of the greater steric hindrance, the first attack proceeded with good site selectivity at position 8.

Synthesis and biocidal activity of some new 2-amino-4,6-diaryl-substituted-pyrimidines

The chalcones (3a-q), derived from 3,5-dibromo-4-hydroxyacetophenone (1a), 3,5-dibromo-2-hydroxyacetophenone (1b), 3-bromo-5-chloro-/5-methyl-2-hydroxyacetophenones (1c,d) and 4-(4'-nitrophenoxy)acetophenone (1c) and prepared by Claisen-Schmidt condensation with different substituted aromatic aldehydes (2a-f) in presence of base, on treatment with guanidine nitrate in ethanol and base give new 2-amino-4,6-diaryl-substituted-pyrimidines (4a-q). The compounds have been screened for their antibacterial and herbicidal activities.

REACTION OF CHALOCONES WITH N-BROMOSUCCINIMIDE. SYNTHESIS OF AURONES

The reaction of 2'-OR-4-R1 chalcone with N-bromosuccinimide is reported.It was found that the structure of the product depends on the nature of the substituents R and R1.The prepared α-bromo-β-methoxydihydrochalcones were converted to the corresponding aurones.