15486-65-4

Upstream product

• 873-76-7 para-Chlorobenzyl alcohol 
• 106-40-1 4-bromo-aniline 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 138714-63-3 (3R,4S)-1-(4-Bromo-phenyl)-4-(4-chloro-phenyl)-3-phenyl-azetidin-2-one 
• 7495-11-6 N-(4-bromophenyl)-2-phenylacetamide 
• 104-88-1 4-chlorobenzaldehyde 
• 138714-63-3 (3S,4S)-1-(4-Bromo-phenyl)-4-(4-chloro-phenyl)-3-phenyl-azetidin-2-one 
• 1601-98-5 1,2-bis(4-bromophenyl)diazene 
• 1335242-67-5 C₂₁H₁₅ClN₂ 
• 1393934-64-9 N-(4-bromophenyl)-N-[(4-chlorophenyl)hydroxymethyl]formamide 
• 195968-98-0 4-bromo-N-(4-chlorobenzyl)aniline 
• 1336883-79-4 1-(4-bromophenyl)-2,2-dichloro-3-(4-chlorophenyl)aziridine 
• 1220110-35-9 N₁,N₂-bis(4-bromophenyl)-1,2-bis(4-chlorophenyl)ethane-1,2-diamine 

Relevant academic research and scientific papers

MODIFICATION OF CRYSTAL PACKING AND MOLECULAR CONFORMATION VIA SYSTEMATIC SUBSTITUTION

Variations in molecular conformation and crystal packing are investigated by systematically altering the substituents on a molecule which has two degrees of conformational freedom.The crystal structures of the heterodisubstituted benzylideneanilines (BA's),p-chloro-N-(p-chlorobenzylidene) aniline (BrCl) and p-bromo-N-(p-chlorobenzylidene) aniline (ClBr) have been determined.The conformations of the two molecules are different from each other but are similar to those found in the crystal structures of the homodisubstituted derivatives with which they are isomorphous: p-bromo-N-(p-bromo-benzylidene) aniline (BrBr) and the orthorombic form of p-chloro-N-(p-chloro-benzylidene)aniline (ClCl) respectively.Because of this isomorphous relationship it is concluded that the substituent on the benzylidene ring plays a crucial role in determining the packing mode of the structure.

Synthesis, growth and characterization of 4-bromo-4′chloro benzylidene aniline - A third order non linear optical material

The organic nonlinear optical material of 4-bromo-4′chloro benzylidene aniline (BCBA) was synthesized and single crystal of BCBA was grown from acetone solution by solvent evaporation method at room temperature. Its three dimensional structure was elucida

Arene diruthenium(II)-mediated synthesis of imines from alcohols and amines under aerobic condition

The utility and selectivity of the newly synthesized dinuclear arene Ru(II) complex were demonstrated towards the synthesis of imines from coupling of alcohols and amines in the aerobic condition. Analytical and various spectral methods have been used to establish the unprecedented formation of the new thiolato-bridged dinuclear ruthenium complex. The molecular structure of the titled complex was evidenced with aid of X-ray crystallographic technique. A wide range of imines were obtained in good-to-excellent yields up to 98% and water as the by-product through an acceptorless dehydrogenative coupling of alcohols with amines. The catalytic reaction operated a concise atom economical without any oxidant with 1 mol% of the catalyst load. Further, the role of base, solvent and catalyst loading of the coupling reaction has been investigated. A plausible mechanism has been described and was found to proceed via the formation of an aldehyde intermediate. Short synthesis of antibacterial drug N-(salicylidene)-2-hydroxyaniline illustrated the utility of the present protocol.

Synthesis and characterization of tetrachloro-1,3-oxazepine derivatives and evaluation of their biological activities

6,7,8,9-Tetrachloro[1,3]oxazepine-1,5-dione derivatives 1b-10b have been synthesized by reacting Schiff bases 1a-10a with tetrachlorophthalic anhydride (TCPA) under (2 + 5 → 7) cycloaddition reaction conditons. All reactions had been monitored using TLC.

Cross dehydrogenative coupling strategy for allylation of benzylanilines promoted by DDQ

A cross dehydrogenative coupling strategy for allylation of benzylanilines promoted by DDQ is reported, which uses nonmetallic quinone DDQ as an oxidant in the allylation of N-benzylanilines under mild conditions. C–C bond with high selectivity and activity was constructed in this reaction and homoallylic amines were obtained with yields of up to 99%.

Montmorillonite as a heterogeneous catalyst in the efficient, mild and one pot synthesis of Schiff bases under solvent-free conditions

A mild and efficient method has been reported for preparation of Schiff base ligands through condensation reaction of various aromatic aldehydes and ketones with different aromatic amines in the presence of montmorillonite as a heterogeneous catalyst under solvent free conditions. The advantages of this friendly, economically, environmentally and mild method are such as; simplicity of the reaction procedure, reusability of catalyst, simple work-up, high product yields and very short reaction times.

Determination of latent transition temperatures of nonmesomorphs by extrapolation method in binary systems

Eight binary systems consisting of mesomorphs and nonmesomorphs (A 1 or A2 + B1 B2, B7, B8) were studied with a view to determine the latent transition temperature (LTT) for the nonmesomorp

A novel catalyst-free one-pot synthesis of some new N-(α- hydroxybenzyl)formamides by treatment of 2,2-dichloroaziridines with dimethyl sulfoxide and water under neutral conditions

A novel, mild, and efficient method is reported for the preparation of new N-(α-hydroxybenzyl)formamides in excellent yields and appropriate reaction times through the reaction of 2,2-dichloroaziridines with aqueous DMSO as the O-donor under neutral condi

GREEN SYNTHESIS OF ARYL ALDIMINES USING ETHYL LACTATE

The present invention relates to a method for preparing aryl aldimines. In particular, the present invention relates to methods of preparing aryl aldimines that uses environmentally friendly solvent systems.

A new Yb3+-catalyzed pinacol and imine-coupling reaction

Ytterbium triflate, Yb(OTf)3, catalyzes the intermolecular reductive homocouplings of imines, aldehydes, and ketones at loadings of 5 mol % in the presence of Mg and Me3SiCl to give isolated yields of up to 95%. Diastereoselectivity of up to 4/96 (dl/meso) is achieved for aromatic aldehydes, up to 100% dl for aliphatic aldehydes, and 100% dl for an intramolecular imine coupling.