154884-62-5

Basic information

• Product Name: 2-Propyn-1-ol, 3-(2-methoxyphenyl)-
• Synonyms: 3-(2-methoxyphenyl)-2-propyn-1-ol;3-(2-Methoxy-phenyl)-prop-2-yn-1-ol;3-(2-methoxy)-phenyl propargyl alcohol;3-(2-Methoxyphenyl)prop-2-yn-1-ol
• CAS NO: 154884-62-5
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 154884-62-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 2-Propyn-1-ol, 3-(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propyn-1-ol, 3-(2-methoxyphenyl)-(154884-62-5)
• EPA Substance Registry System: 2-Propyn-1-ol, 3-(2-methoxyphenyl)-(154884-62-5)

Safety Data

• Hazardous Substances Data: 154884-62-5(Hazardous Substances Data)

Upstream product

• 529-28-2 4-iodoanisol 
• 107-19-7 propargyl alcohol 
• 578-57-4 2-bromoanisole 
• 850079-46-8 [3-(2-methoxy-phenyl)-prop-2-ynyloxy]-trimethyl-silane 
• 50-00-0 formaldehyd 
• 90585-32-3 1,1-dibromo-2-(2-methoxyphenyl)ethene 

Downstream Products

• 154884-63-6 3-(2-methoxyphenyl)propiolaldehyde 
• 913827-73-3 1-(3-bromo-prop-1-ynyl)-2-methoxybenzene 
• 913827-66-4 1,6-dihydro-1-[3-(2-methoxyphenyl)-2-propynyl]-6-oxo-2-pyridinecarbonitrile 
• 705246-70-4 O-(3-(2-methoxyphenyl)-2-propynyl)hydroxylamine 
• 287108-70-7 5-bromo-2-({4-[3-(2-methoxy-phenyl)-prop-2-ynyloxy]-benzenesulfonyl}-methyl-amino)-3-methyl-benzoic acid methyl ester 
• 1235983-68-2 diisopropyl 1-(3-(2-methoxyphenyl)-2-propyn-1-yl)hydrazine-1,2-dicarboxylate 
• 1146969-04-1 diethyl 5-formyl-4-(2-methoxyphenyl)furan-2,3-dicarboxylate 
• 1241859-89-1 diethyl 4-(2-methoxyphenyl)-5-methylfuran-2,3-dicarboxylate 
• 1367053-90-4 (R)-2-(2-methoxyphenyl)-4-(nitromethyl)-4H-chromene-3-carbaldehyde 
• 1373340-57-8 methyl 2-((3-(2-methoxyphenyl)prop-2-yn-1-yl)oxy)-1H-indole-3-carboxylate 
• 1276045-69-2 (Z)-1-[3-ethoxy-1-(4-methoxyphenyl)prop-1-en-1-yl]-2-methoxybenzene 
• 1370521-21-3 (Z)-1-[3-ethoxy-1-(3-methoxyphenyl)prop-1-enyl]-2-methoxybenzene 

Relevant articles and documents

Unexpected Course of the Reaction of 1,3-Bis(dimethylamino)trimethinium Perchlorate with 3-Substituted Prop-2-ynals Leading to 1-Aryl-2,4,6-triformylbenzenes

Reaction of 1,3-bis(dimethylamino)trimethinium perchlorate (1) with 3-substituted prop-2-ynals (4) in acetic anhydride at the presence of ZnBr2 gives upon hydrolysis 1-substituted 2,4,6-triformylbenzenes (6) in low to moderate yield. This reaction is restricted to prop-2-ynals bearing electron rich aromatic substituents at the 3-position.

One-pot synthesis of 3-substituted-4H-[1,2,3] triazolo[5,1-c][1,4]oxazin-6(7H)-ones from propargyl alcohols, chloroacetyl chloride, and sodium azide

An efficient, one-pot synthesis of 3-substituted-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-6(7H)-ones is developed via sequential esterification, substitution, and 1,3-dipolar cycloaddition processes of various propargyl alcohols, chloroacetyl chloride, and so

Bi(OTf)3 catalyzed synthesis of acyclic β-sulfanyl ketones via a tandem Meyer-Schuster rearrangement/conjugate addition reaction

A new strategy to prepare acyclic β-carbonyl thioethers from propargyl alcohols and sulfur nucleophiles is reported. The investigation of the reaction substrates scope indicated that primary 3-aryl propargyl alcohols and thiols underwent the transformation smoothly. The reaction probably proceeded a Bi(OTf)3-catalyzed tandem Meyer-Schuster rearrangement of 3-aryl propargyl alcohol, followed by a thiol Michael conjugate addition of thiols to in situ generated α, β-unsaturated ketones. The method was 100% atom economic, high-yielding, and easy to handle, making it a valuable method for the construction of β-carbonyl sulfides.