154912-68-2Relevant academic research and scientific papers
Synthesis of the FG ring fragment of pectenotoxins 1-9
Heapy, Amanda M.,Brimble, Margaret A.
experimental part, p. 5424 - 5431 (2010/08/13)
The synthesis of the FG ring fragment common to pectenotoxins 1-9 is reported.The successful, convergent synthesis relied on high yielding routes to access two key intermediates; aldehyde 1 and phosphonium salt 2.A Z-selective Wittig reaction gave access
Synthesis of the FG fragment of the pectenotoxins
Heapy, Amanda M.,Wagner, Thomas W.,Brimble, Margaret M.
, p. 2359 - 2362 (2008/03/13)
The synthesis of the FG subunit of the pectenotoxins is reported herein. The synthesis hinges on the preparation of an appropriately functionalized acyclic precursor using a Z-selective Wittig reaction. Further elaboration using two sequential cyclization
A total synthesis of the unique tris-oxazole macrolide ulapualide a produced by the marine nudibranch Hexabranchus sanguineus
Chattopadhyay, Shital K.,Pattenden, Gerald
, p. 2429 - 2454 (2007/10/03)
A total synthesis of ulapualide A (1), whose relative stereochemistry was assigned on the basis of an earlier molecular mechanics study of its hypothetical metal chelated complex 9, is described. The synthesis is based on: i, elaboration of the double fun
Synthetic studies towards novel tris-oxazole based macrolides of marine origin. Stereocontrolled synthesis of the C20 - C35 fragment in ulapualide A
Chattopadhyay, Shital K.,Pattenden, Gerald
, p. 5271 - 5274 (2007/10/02)
The C20 - C35 subunit 3 in ulapualide A 1 has been synthesised in enantiomerically pure form using a combination of the Evans aldol reaction, controlled ring opening reactions of chiral epoxides, and Brown's asymmetric allylboration reaction, to set up th
Studies directed towards the synthesis of rapamycin: Stereoselective synthesis of C-1 to C-15 segment
Rama Rao,Desibhatla, Vidyanand
, p. 7111 - 7114 (2007/10/02)
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described.
