15495-64-4Relevant academic research and scientific papers
Amino acid catalyzed synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives
Mustaque, K. Mohammed,Subramani,Shabeer,Thajudeen,Ahamed, V. S. Jamal
, p. 246 - 250 (2018)
A simple, convenient and facile approach for the synthesis of a series of 2,3-dihydroquinazolin-4(1H)-ones in an environmentally benign method has been developed. This method involves a direct cyclocondensation of 2-aminobenzamide with aromatic aldehydes and ketones using aspartic acid as a catalyst in water.
Facile and efficient protocols for C–C and C–N bond formation reactions using a superparamagnetic palladium complex as reusable catalyst
Karimi Zarchi, Mohammad Ali,Darbandizadeh Mohammad Abadi, Seyed Shahab Addin
, p. 2605 - 2639 (2019/02/13)
Abstract: Facile and efficient protocols for some multicomponent coupling reactions such as the Suzuki reaction and synthesis of polyhydroquinoline and 2,3-dihydroquinazoline-4-(1H)-one derivatives using a superparamagnetic palladium complex as catalyst have been developed. Graphical abstract: [Figure not available: see fulltext.].
KOH/DMSO: A basic suspension for transition metal-free Tandem synthesis of 2,3-dihydroquinazolin-4(1H)-ones
Dutta, Apurba,Damarla, Krishnaiah,Bordoloi, Ankur,Kumar, Arvind,Sarma, Diganta
supporting information, p. 1614 - 1619 (2019/05/24)
A novel protocol for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones from 2-aminobenzamides and aldehyde derivatives catalyzed by KOH/DMSO suspension has been developed. The present transition metal free methodology is operationally simple, scalable and varieties of 2,3-dihydroquinazolin-4(1H)-one derivatives were obtained in good to excellent yields in short reaction times.
Expeditious synthesis of 2,3-dihydroquinazolin-4(1H)-ones in aqueous medium using thiamine hydrochloride (VB1) as a mild, efficient, and reusable organocatalyst
Devi, Jutika,Kalita, Subarna Jyoti,Deka, Dibakar Chandra
supporting information, p. 1601 - 1609 (2017/09/08)
A simple and straightforward synthesis of 2,3-dihydroquinazolin-4(1H)-ones is developed by reacting anthranilamide with various aldehydes or ketones under mild reaction conditions, using thiamine hydrochloride as a cost-effective, readily available, and green catalyst in water. Simple purification process, high yields within short reaction time, wide substrate scope, operational simplicity, and reusability of the catalyst up to three cycles enrich the applicability of the protocol.
Glycerol based ionic liquid with a boron core: A new highly efficient and reusable promoting medium for the synthesis of quinazolinones
Safaei, Hamid Reza,Shekouhy, Mohsen,Shafiee, Vahid,Davoodi, Mansooreh
, p. 139 - 144 (2013/04/24)
A highly efficient and environmental benign procedure for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones via the condensation of carbonyl compounds with 2-aminobenzamide using a glycerol based ionic liquid with a boron core as a new and reusable promoting medium is described. A broad range of substrates including aldehydes and ketone were condensed with 2-aminobenzamide. All reactions are completed in short times and the products are obtained in good to excellent yields. The reaction medium could be recycled and reused several times without any loss of efficiency. Moreover, presented procedure has been applied successfully for the synthesis of some novel bis(pyrazolinone) derivatives.
Tandem synthesis of 2,3-dihydroquinazolin-4(1H)-ones on grinding under solvent-free conditions
Ding, Quan-Sheng,Zhang, Ji-Lei,Chen, Jiu-Xi,Liu, Miao-Chang,Ding, Jin-Chang,Wu, Hua-Yue
experimental part, p. 375 - 380 (2012/06/04)
Citric acid promoted synthesis of a mini-library 2,3-dihydroquinazolin- 4(1H)-ones with good to excellent yields is achieved by tandem reaction of anthranilamides (or anthranilhydrazides) with aldehydes on grinding at room temperature under solvent-free conditions. This method has notable advantages in terms of simple workup, short reaction time, cost-effective, and environmentally benign. Copyright
Gallium(III) triflate-catalyzed one-pot selective synthesis of 2,3-dihydroquinazolin-4(1H)-ones and quinazolin-4(3H)-ones
Chen, Jiuxi,Wu, Dengze,He, Fei,Liu, Miaochang,Wu, Huayue,Ding, Jinchang,Su, Weike
, p. 3814 - 3818 (2008/09/21)
A series of 2,3-dihydroquinazolin-4(1H)-ones and quinazolin-4(3H)-ones have been synthesized in good to excellent yields and high selectivity by one-pot reaction using isatoic anhydride, ammonium acetate (or amines), and aldehydes in ethanol or in DMSO under mild conditions, respectively. The reaction was efficiently promoted by 1 mol % Ga(OTf)3 and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity.
