15500-96-6

Basic information

• Product Name: 1-(2-Chlorophenyl)-3-methylurea
• Synonyms: 1-(2-Chlorophenyl)-3-methylurea
• CAS NO: 15500-96-6
• Molecular Formula: C₈H₉ClN₂O
• Molecular Weight: 184.6229
• Mol File: 15500-96-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 260.3°Cat760mmHg
• Flash Point: 111.2°C
• Appearance: /
• Density: 1.288g/cm³
• Vapor Pressure: 0.0123mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 1-(2-Chlorophenyl)-3-methylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Chlorophenyl)-3-methylurea(15500-96-6)
• EPA Substance Registry System: 1-(2-Chlorophenyl)-3-methylurea(15500-96-6)

Safety Data

• Hazardous Substances Data: 15500-96-6(Hazardous Substances Data)

Usage

General Description

1-(2-Chlorophenyl)-3-methylurea, also known as Diuron, is a chemical compound commonly used as a herbicide to control weeds in various agricultural and non-agricultural settings. It inhibits photosynthesis in plants by disrupting the electron transport chain, ultimately leading to their death. Diuron is a white, crystalline solid that is sparingly soluble in water and is considered to have a low to moderate toxicity to humans. It is classified as a possible human carcinogen by the United States Environmental Protection Agency (EPA) and has been banned for use in some countries due to its potential environmental and health hazards. Overall, the use of 1-(2-Chlorophenyl)-3-methylurea has sparked considerable debate and concerns regarding its safety and impacts on human and environmental health.

InChI:InChI=1/C8H9ClN2O/c1-10-8(12)11-7-5-3-2-4-6(7)9/h2-5H,1H3,(H2,10,11,12)

Upstream product

• 3320-83-0 o-chlorophenyl isocyanate 
• 372-09-8 cyanoacetic acid 

Downstream Products

• 36909-27-0 C₉H₈Cl₂N₂O₂ 
• 176379-65-0 6-amino-1-(2-chloro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione 
• 176379-66-1 5,6-diamino-1-(2-chlorophenyl)-3-methyl-2,4 (1H, 3H)-pyrimidinedione 
• 101488-98-6 C₁₄H₂₀ClN₃O₂ 
• 112502-82-6 2-tert-Butyl-6-(2-chloro-phenyl)-4-methyl-[1,2,4,6]thiatriazinane-3,5-dione 
• 112502-81-5 2-(2-Chloro-phenyl)-6-(1,1-dimethyl-propyl)-4-methyl-1-oxo-1λ⁴-[1,2,4,6]thiatriazinane-3,5-dione 

Relevant articles and documents

1-arylpyrimidine derivatives and pharmaceutical use thereof

The present invention relates to 1-arylpyrimidine derivatives represented by general formula (I): STR1 wherein R1 is H, alkyl or aralkyl; Ar is 1-naphthyl, or a substituted or unsubstituted phenyl group; R4 is a substituted phenyl, a substituted styryl, 1-methylcyclohexyl, 4-methylcyclohexyl, 4-oxo-4H-pyran-2-yl or 2-oxo-2H-pyran-5-yl group; R5 and R6 are each independently H or alkyl; R3 is H, and R7 and R8 are combined together to be oxo, or else R3 and R7 are combined together to be another direct bond, and R5 and R8 are combined together to be a direct bond, or pharmaceutically acceptable salts thereof; and methods for treating allergic diseases with such compounds.