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Usage

Uses

Used in Agricultural and Non-Agricultural Settings:
1-(2-Chlorophenyl)-3-methylurea is used as a herbicide for controlling weeds in various agricultural and non-agricultural settings. It is applied to inhibit the photosynthesis process in plants by disrupting the electron transport chain, which ultimately leads to the death of the weeds, thereby promoting the growth of desired crops or maintaining the aesthetics of non-agricultural areas.
However, it is important to note that the use of 1-(2-Chlorophenyl)-3-methylurea has sparked considerable debate and concerns regarding its safety and impacts on human and environmental health. As a result, it has been banned in some countries to mitigate potential risks.

InChI:InChI=1/C8H9ClN2O/c1-10-8(12)11-7-5-3-2-4-6(7)9/h2-5H,1H3,(H2,10,11,12)

Upstream product

• 3320-83-0 o-chlorophenyl isocyanate 
• 372-09-8 cyanoacetic acid 

Downstream Products

• 176379-65-0 6-amino-1-(2-chloro-phenyl)-3-methyl-1H-pyrimidine-2,4-dione 
• 176379-66-1 5,6-diamino-1-(2-chlorophenyl)-3-methyl-2,4 (1H, 3H)-pyrimidinedione 
• 112502-81-5 2-(2-Chloro-phenyl)-6-(1,1-dimethyl-propyl)-4-methyl-1-oxo-1λ⁴-[1,2,4,6]thiatriazinane-3,5-dione 
• 112502-82-6 2-tert-Butyl-6-(2-chloro-phenyl)-4-methyl-[1,2,4,6]thiatriazinane-3,5-dione 
• 101488-98-6 C₁₄H₂₀ClN₃O₂ 
• 36909-27-0 C₉H₈Cl₂N₂O₂ 

Relevant academic research and scientific papers

1-arylpyrimidine derivatives and pharmaceutical use thereof

The present invention relates to 1-arylpyrimidine derivatives represented by general formula (I): STR1 wherein R1 is H, alkyl or aralkyl; Ar is 1-naphthyl, or a substituted or unsubstituted phenyl group; R4 is a substituted phenyl, a substituted styryl, 1-methylcyclohexyl, 4-methylcyclohexyl, 4-oxo-4H-pyran-2-yl or 2-oxo-2H-pyran-5-yl group; R5 and R6 are each independently H or alkyl; R3 is H, and R7 and R8 are combined together to be oxo, or else R3 and R7 are combined together to be another direct bond, and R5 and R8 are combined together to be a direct bond, or pharmaceutically acceptable salts thereof; and methods for treating allergic diseases with such compounds.