155006-66-9Relevant academic research and scientific papers
Synthesis and analytical profile of the new potent antibronchospastic agent 7-[(2,2-dimethyl)propyl]-1-methyl xanthine
Agostini,Bonacchi,Coppini,Di Marco,Paoli,Toja
, p. 684 - 688 (2007/10/02)
7-[(2,2-Dimethyl)propyl]-1-methyl xanthine (CAS 155006-67-0, MX2/120) is a new potent antibronchospastic agent with negligible side effects. The synthesis involves the alkylation of 3-benzyl-1-methyl xanthine with neopentyl bromide followed by removal of
A new class of antibronchospastic agents: 7-(2,2-dimethyl)propyl substituted xanthines
Bonacchi,Agostini,Di Marco,Borgianni,Ballati,Boni,Castellucci,Evangelista,Toja
, p. 333 - 339 (2007/10/02)
A series of 7-(2,2-dimethyl)propyl substituted xanthines were synthesized and tested for their antibronchospastic activity in comparison with theophylline. In vitro, the inhibition of carbachol-induced increase in bronchial tone was determined. In vivo, t
