1550107-48-6Relevant articles and documents
Pd0-catalyzed methyl transfer on nucleosides and oligonucleotides, envisaged as a PET tracer
James, Damien,Escudier, Jean-Marc,Szlosek-Pinaud, Magali,Fouquet, Eric
, p. 13654 - 13665 (2013)
The methyl transfer reaction from activated monomethyltin, via a modified Stille coupling reaction, was studied under ligandless conditions on fully deprotected 5'-modified nucleosides and one dinucleotide. The reaction was optimized to proceed in a few minutes and quantitative yield, even under dilute conditions, thus affording a rapid and efficient new method for oligonucleotide labelling with carbon-11.