155036-84-3

Upstream product

• 162936-40-5 (3aS,4S,6R,6aR)-6-[6-Amino-2-(5-phenyl-pent-1-ynyl)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid ethylamide 
• 155036-85-4 (2S,3S,4R,5R)-5-(6-Amino-2-ethynyl-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide 
• 1823-14-9 5-phenyl-1-pentyne 
• 141018-29-3 2-iodo-5'-N-ethylcarboxamidoadenosine 
• 162936-24-5 N-ethyl-1'-deoxy-1'-(6-amino-2-iodo-9H-purin-9-yl)-2',3'-O-isopropylidene-β-D-ribofuranuronamide 

Relevant academic research and scientific papers

Potent and selective ligands for adenosine binding sites

A number of selective ligands for the different binding sites of adenosine have been synthesized and tested in several pharmacological models. The aim of these synthetic efforts is both to improve the knowledge of structure-activity relationships in the adenosine-related biological systems and to develop drugs from some of these molecules.

2-Aralkynyl and 2-Heteroalkynyl Derivatives of Adenosine-5'-N-ethyluronamide as Selective A2a Adenosine Receptor Agonists

A series of new 2-aralkynyl and 2-heteroaralkynyl derivatives of NECA were synthesized and studied in binding and functional assays to assess their potency for the A2a compared to A1 adenosine receptors.Compounds bearing an aromatic