155050-17-2 Usage
Description
(R)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID is a chemical compound with the molecular formula C9H11NO3, derived from the amino acid alanine and featuring a pyridine group. (R)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID is characterized by its unique chemical structure and properties, making it a promising building block for the synthesis of pharmaceuticals and other organic compounds.
Uses
Used in Pharmaceutical Industry:
(R)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID is used as a building block for the synthesis of new drugs and biologically active molecules. Its unique chemical structure and properties contribute to the development of innovative pharmaceuticals with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID serves as a key component in the design and synthesis of novel compounds with potential therapeutic effects. Its versatility allows for the exploration of various chemical modifications to enhance the pharmacological properties of the resulting molecules.
Used in Biological Research:
(R)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID may have biological activity, making it a subject of interest for biological research. Studies on its potential role in various biological processes can provide valuable insights into its mechanisms of action and pave the way for the discovery of new therapeutic targets and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 155050-17-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,0,5 and 0 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 155050-17:
(8*1)+(7*5)+(6*5)+(5*0)+(4*5)+(3*0)+(2*1)+(1*7)=102
102 % 10 = 2
So 155050-17-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2/c9-7(4-8(11)12)6-2-1-3-10-5-6/h1-3,5,7H,4,9H2,(H,11,12)/t7-/m1/s1
155050-17-2Relevant articles and documents
Iridium-catalysed C-H borylation of β-aryl-aminopropionic acids
MacDonald, Simon J. F.,Nortcliffe, Andrew,Robinson, Henry,Simelis, Klemensas,Stillibrand, Joe
supporting information, p. 6696 - 6701 (2020/09/21)
Iridium-catalysed catalytic, regioselective C-H borylation of β-aryl-aminopropionic acid derivatives gives access to 3,5-functionalised protected β-aryl-aminopropionic acid boronates. The synthetic versatility of these new boronates is demonstrated through sequential one-pot functionalisation reactions to give diverse building blocks for medicinal chemistry. The C-H borylation is also effective for dipeptide substrates. We have exemplified this methodology in the synthesis of a pan αv integrin antagonist.
Burkholderia cepacia lipase is an excellent enzyme for the enantioselective hydrolysis of β-heteroaryl-β-amino esters
Tasnadi, Gabor,Forro, Eniko,Fueloep, Ferenc
experimental part, p. 1771 - 1777 (2009/12/28)
The enantioselective (E >200) lipase PS-catalysed hydrolysis of β-heteroaryl-β-amino esters is described. The reactions were performed with H2O (0.5 equiv) in either diisopropyl ether or tert-butyl methyl ether at 25 °C. The resulting β-heteroaryl-substituted β-amino acid enantiomers were formed in high enantiomeric excess (ee ≥ 97%) and in good yield (≥40%).
Structure-activity relationships of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists
Guo, Zhiqiang,Wu, Dongpei,Zhu, Yun-Fei,Tucci, Fabio C.,Regan, Collin F.,Rowbottom, Martin W.,Struthers, R. Scott,Xie, Qiu,Reijmers, Shelby,Sullivan, Susan K.,Sai, Yang,Chen, Chen
, p. 3685 - 3690 (2007/10/03)
SAR studies of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists resulted in potent compounds. The best compound from the series had a binding affinity of 2 nM.
