155125-22-7

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 
• 155236-64-9 (R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-((2S,3R)-3-propyl-oxiranyl)-propan-1-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 138760-91-5 (R)-2-(t-butyldimethylsilyloxymethyl)-3(Z)-hepten-1-ol 
• 138760-89-1 (Z)-(S)-2-(Acetoxymethyl)hept-3-en-1-ol 

Downstream Products

• 138761-06-5 (4R,5R)-5-Benzyloxymethoxymethyl-4-butyl-2,2-dimethyl-[1,3]dioxane 

Relevant academic research and scientific papers

Stereoselective epoxidation of asymmetrized 2-alkenyl-1,3-propanediols

Asymmetrized 2-alkenyl 1,3-propanediols are stereoselectively epoxidized to the same main diastereoisomer both with 3-chloroperbenzoic acid and the VO(acac)2/t-butyl hydroperoxyde system. Using the latter epoxidating reagent in combination with a protection-deprotection sequence involving the two homoallylic hydroxy groups, all the four cis epoxides were easily achieved in stereoisomeric pure from starting from a single common (Z) precursor.