138761-06-5Relevant academic research and scientific papers
Stereoselective epoxidation of asymmetrized 2-alkenyl-1,3-propanediols
Guanti,Banfi,Narisano,Thea
, p. 6943 - 6946 (1991)
Asymmetrized 2-alkenyl 1,3-propanediols are stereoselectively epoxidized to the same main diastereoisomer both with 3-chloroperbenzoic acid and the VO(acac)2/t-butyl hydroperoxyde system. Using the latter epoxidating reagent in combination with a protection-deprotection sequence involving the two homoallylic hydroxy groups, all the four cis epoxides were easily achieved in stereoisomeric pure from starting from a single common (Z) precursor.
