155142-81-7

Basic information

• Product Name: N-METHYL-N-BUTYL-11-BROMO-UNDECANAMIDE
• Synonyms: N-METHYL-N-BUTYL-11-BROMO-UNDECANAMIDE
• CAS NO: 155142-81-7
• Molecular Formula: C16H32BrNO
• Molecular Weight: 334.34
• Mol File: 155142-81-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-METHYL-N-BUTYL-11-BROMO-UNDECANAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-N-BUTYL-11-BROMO-UNDECANAMIDE(155142-81-7)
• EPA Substance Registry System: N-METHYL-N-BUTYL-11-BROMO-UNDECANAMIDE(155142-81-7)

Safety Data

• Hazardous Substances Data: 155142-81-7(Hazardous Substances Data)

Upstream product

• 110-68-9 N-n-butyl-N-methylamine 
• 2834-05-1 11-bromoundecanoic acid 

Downstream Products

• 155143-02-5 N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide 
• 98007-99-9 11-(3,17β-dihydroxy-estra-1,3,5(10)-triene-7α-yl)-undecanoic acid n-butyl-methyl-amide 

Relevant articles and documents

STEROIDS FOR CANCER TREATMENT

The present invention relates to novel compounds which are 7α-substituted 17-alkylene-16α-hydroxy steroidal estrogens. This invention specifically relates to estrogen derivatives which contain 7α-substituents and which exhibit anti-estrogenic properties. The present invention also relates to use of said compounds as a medicament, and for the treatment of estrogen dependent disorders, a pharmaceutical composition comprising one or more of said compounds and a method of treatment.

An expeditious route to 7α-substituted estradiol derivatives

6-Ketoestradiol derivatives are converted in 7α-alkyl substituted estradiol derivatives selectively by alkylation of the generated enolate followed by deoxygenation-deprotection with BF3·Et2O/Et3SiH.