155184-82-0

Basic information

• Product Name: 6-Amino-2-chloro-3-methyl-benzoic acid
• Synonyms: 6-Amino-2-chloro-3-methyl-benzoic acid
• CAS NO: 155184-82-0
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.60762
• Mol File: 155184-82-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Amino-2-chloro-3-methyl-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Amino-2-chloro-3-methyl-benzoic acid(155184-82-0)
• EPA Substance Registry System: 6-Amino-2-chloro-3-methyl-benzoic acid(155184-82-0)

Safety Data

• Hazardous Substances Data: 155184-82-0(Hazardous Substances Data)

Usage

General Description

6-Amino-2-chloro-3-methyl-benzoic acid is a chemical compound with the molecular formula C8H8ClNO2. It is a derivative of benzoic acid and contains an amino group, a chlorine atom, and a methyl group attached to a benzene ring. 6-Amino-2-chloro-3-methyl-benzoic acid is used in the synthesis of pharmaceuticals and agrochemicals, and it also has potential applications in the field of organic chemistry as a building block for more complex molecules. 6-Amino-2-chloro-3-methyl-benzoic acid is a white to off-white crystalline powder and is sparingly soluble in water. Its use and handling should comply with all relevant regulations and safety precautions to minimize the risk of adverse effects on human health and the environment.

Upstream product

• 155184-79-5 N-(3-chloro-4-methyl-phenyl)-2-hydroxyimino-acetamide 
• 7745-89-3 3-chloro-4-methylaniline hydrochloride 
• 53003-18-2 4-chloro-5-methyl-1H-indole-2,3-dione 

Downstream Products

• 450407-83-7 2-(N-tert-butyloxycarbonyl)amino-5-methyl-6-chlorobenzoic acid 
• 450407-84-8 methyl 2-(N-tert-butyloxycarbonyl)amino-5-methyl-6-chlorobenzoate 
• 342411-56-7 methyl 2-amino-5-methyl-6-chlorobenzoate 
• 15068-35-6 2-chloro-3-methylbenzoic acid 

Relevant articles and documents

FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF

AbstractNovel compounds of the following formula (I) and pharmacologically acceptable salt and esters thereof can modulate LXR function and as a result show excellent anti-arteriosclerotic and anti-inflammatory activity:wherein:A represents aryl or heteroaryl;R1, R2 and R3 are the same or different and each represents hydrogen, hydroxyl, nitro, cyano, amino, halogen, carboxy, carbamoyl, mercapto, alkyl, haloalkyl, alkylcarbonyloxy, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, dialkylamino, alkylcarbonylamino, N-(alkylcarbonyl)-N-(alkyl)amino, alkoxycarbonylamino, N-(alkoxycarbonyl)-N-(alkyl)amino, alkylsulfonylamino, N-(alkylsulfonyl)-N-(alkyl)amino, haloalkylsulfonylamino, N-(haloalkylsulfonyl)-N-(alkyl)amino, alkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl group, or R1 and R2 together are alkylenedioxy;R4 and R5 are the same or different and each represents hydrogen, hydroxyl, amino, halogen, mercapto, alkyl, haloalkyl, alkoxy, alkoxycarbonyl or alkylthio;X represents hydrogen, hydroxyl, halogen, alkoxy or haloalkoxy; andY represents an optionally substituted alkyl, cycloalkyl, heterocyclyl, aryl, cycloalkylalkyl, heterocyclylalkyl or aralkyl group.

Synthesis of 3,4-Dihydro-1,4-ethenonaphthalen-2(1H)-ones by Benzyne Cycloadditions.

As part of a project on the photochemistry of 3,4-dihydro-1,4-ethanonaphthalen-2(1H)-ones (benzobicyclooctanones), we were interested in preparing the model 9-ene precursors shown in Scheme 1.On the basis of previous work, it was envisaged that the