155190-92-4

Upstream product

• 286408-85-3 (3aR,5R,6R,6aR)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]-2,2,6-trimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol 
• 159312-42-2 (3aR,5R,6R,6aR)-6-Benzyloxy-5-benzyloxymethyl-2,2,6-trimethyl-tetrahydro-furo[2,3-d][1,3]dioxole 
• 100-39-0 benzyl bromide 
• 24467-33-2 (3aR,5R,6R,6aR)-5-(hydroxymethyl)-2,2,6-trimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol 
• 286408-87-5 (2R,3R)-2,4-Bis-benzyloxy-3-hydroxy-2-methyl-butyraldehyde 

Downstream Products

• 42933-13-1 2-C-methyl-D-erythritol 

Relevant academic research and scientific papers

Synthesis of tritium labelled 2-C-methyl-D-erythritol, a useful substrate for the elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis

Free 2,C-methyl-D-erythritol is utilised for isoprenoid biosynthesis by Escherichia coli mutants lacking the two first enzymes of the methylerythritol phosphate pathway, the deoxyxylulose phosphate synthase and isomero-reductase. For feeding experiments, this tetrol was synthesised with an overall 43% yield from readily available 1,2-O-isopropylidene-α-D- xylofuranose, including the possibility of tritium labelling. (C) 2000 Elsevier Science Ltd.