1552-17-6

Basic information

• Product Name: 2-Nitro-5-phenoxyaniline
• Synonyms: (2-Nitro-6-phenoxyphenyl)amine;Benzenamine, 2-nitro-5-phenoxy-
• CAS NO: 1552-17-6
• Molecular Formula: C₁₂H₁₀N₂O₃
• Molecular Weight: 230.2194
• Mol File: 1552-17-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 148-150 °C
• Boiling Point: 377.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.322±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -1.05±0.25(Predicted)
• CAS DataBase Reference: 2-Nitro-5-phenoxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Nitro-5-phenoxyaniline(1552-17-6)
• EPA Substance Registry System: 2-Nitro-5-phenoxyaniline(1552-17-6)

Safety Data

• Hazardous Substances Data: 1552-17-6(Hazardous Substances Data)

Usage

General Description

2-Nitro-5-phenoxyaniline is a chemical compound with the molecular formula C12H10N2O3. It is a nitroaniline derivative that consists of a nitro group and a phenoxy group attached to an aniline moiety. 2-Nitro-5-phenoxyaniline is often used in the synthesis of various organic substances and pharmaceuticals. It has potential applications in the field of medicine and drug development due to its unique chemical structure and properties. However, it is important to handle this chemical with caution as it may pose risks to human health and the environment if not properly managed and controlled.

Upstream product

• 1635-61-6 5-chloro-2-nitroaniline 
• 108-95-2 phenol 
• 13940-96-0 2-Amino-4-phenoxyaniline 
• 2369-11-1 5-fluoro-2-nitroaniline 
• 620-88-2 4-nitrophenyl phenyl ether 
• 5443-33-4 N-(5-chloro-2-nitrophenyl)acetamide 
• 100-67-4 potassium phenolate 
• 5228-61-5 5-bromo-2-nitroaniline 

Downstream Products

• 59011-05-1 C₂₃H₂₁N₃O₄S 
• 1246788-08-8 C₂₀H₁₆N₂O₂ 
• 63471-10-3 acetic acid-(2-nitro-5-phenoxy-anilide) 
• 501908-78-7 5-phenoxybenzo-2,1,3-oxadiazole N-oxide 
• 59011-03-9 C₂₁H₂₅N₃O₄S 
• 59011-02-8 e OOO-XOX 
• 43155-38-0 methyl (5-phenoxy-1H-benzo[d]imidazol-2-yl)carbamate 
• 13940-96-0 2-Amino-4-phenoxyaniline 
• 1552-16-5 4-Nitro-3-methylmercapto-diphenylaether 
• 58306-45-9 2-cyclohexanecarboxamido-4-phenoxyaniline 
• 58306-43-7 2-Amino-5-phenoxybutyranilid 
• 58306-44-8 2-benzamido-4-phenoxyaniline 
• 58306-42-6 2-Amino-5-phenoxypropionanilid 
• 37984-21-7 C,C,C-Trifluoro-N-(2-nitro-5-phenoxy-phenyl)-methanesulfonamide 

Relevant articles and documents

PqsR INVERSE AGONISTS

The present invention relates to a compound according to general formula (I), which acts as an inhibitor of PqsR (the currently only known receptor for the Pseudomonas Quinolone Signal (PQS)); to a pharmaceutical composition containing one or more of the compound(s) of the invention; to a combination preparation containing at least one compound of the invention and at least one further active pharmaceutical ingredient; and to uses of said compound(s), including the use as a medicament, e.g. the use in the treatment or prophylaxis of a bacterial infection, especially a Pseudomonas aeruginosa or Burkholderia infection.

Ultrasound synthesis of diaryl ethers

2,2-Bis[4-(4-nitroaryl)phenyl]hexafluoropropanes appropriate for the synthesis of monomers were prepared by the reaction of 2,2-bis[4-hydroxyphenyl)hexafluoropropane with 1-chloro-4-nitrobenzenes under ultrasonic activation.

Synthesis of 5-substituted and 5.6-disubstituted-2-phenoxymethyl benzimidazoles

5-Substituted and 5,6-disubstituted-2-phenoxymethyl benzimidazoles [Via to VI-I] were synthesized from 5-substituted and 4,5-disubstituted ortho phenylene diamines (OPD) [IV] with simple or substituted phenoxyacetic acids [V] in 4N HCl. Synthesized compou