1552321-12-6

Basic information

• Product Name: 2-[4-[[2-(benzothiophen-2-yl)-5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl]amino]-2-fluorophenyl]acetic acid
• Synonyms: 2-[4-[[2-(benzothiophen-2-yl)-5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl]amino]-2-fluorophenyl]acetic acid
• CAS NO: 1552321-12-6
• Molecular Weight: 483.544
• Mol File: 1552321-12-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-[[2-(benzothiophen-2-yl)-5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl]amino]-2-fluorophenyl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-[[2-(benzothiophen-2-yl)-5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl]amino]-2-fluorophenyl]acetic acid(1552321-12-6)
• EPA Substance Registry System: 2-[4-[[2-(benzothiophen-2-yl)-5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl]amino]-2-fluorophenyl]acetic acid(1552321-12-6)

Safety Data

• Hazardous Substances Data: 1552321-12-6(Hazardous Substances Data)

Upstream product

• 87466-23-7 2,4-dichloro-7,8-dihydro-6H-thiopyrano<3,2-d>pyrimidine 
• 87466-56-6 7,8-dihydro-2,4-dihydroxy-6H-thiopyrano<3,2-d>pyrimidine 
• 1552321-06-8 methyl 2-[4-[(2-chloro-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl)amino]-2-fluorophenyl]acetate 
• 87466-55-5 7,8-dihydro-4-hydroxy-2-methylthio-6H-thiopyrano<3,2-d>pyrimidine 
• 38555-41-8 methyl 3-oxo-2,3,4,5-tetrahydro-6H-thiopyran-2-carboxylate 
• 38555-40-7 methyl 4-{[2-(methyloxy)-2-oxoethyl]thio}butanoate 

Relevant articles and documents

Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors

A PDE4B subtype selective inhibitor is expected to have a wider therapeutic window than non-selective PDE4 inhibitors. In this Letter, two series of 7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives and 5,5-dioxo-7,8- dihydro-6H-thiopyrano[3,2-d]pyri