87466-23-7

Usage

Uses

Used in Medicinal Chemistry:
2,4-dichloro-7,8-dihydro-6H-Thiopyrano[3,2-d]pyrimidine is utilized as a compound of interest in medicinal chemistry for its potential to contribute to the development of new pharmaceuticals. Its unique structure may allow it to interact with biological targets in ways that could lead to the creation of novel therapeutic agents.
Used in Drug Development:
In the pharmaceutical industry, 2,4-dichloro-7,8-dihydro-6H-Thiopyrano[3,2-d]pyrimidine is used as a starting material or a building block in the synthesis of new drugs. Its chemical properties and structural features make it a candidate for further exploration and optimization to enhance its pharmacological profile, potentially leading to the discovery of effective treatments for various diseases.
Used in Research and Development:
2,4-dichloro-7,8-dihydro-6H-Thiopyrano[3,2-d]pyrimidine serves as a subject of research in academic and industrial laboratories. Scientists are interested in its synthesis and characterization to better understand its properties and to explore its potential applications in various fields, including but not limited to, drug discovery, chemical biology, and materials science.

InChI:InChI=1/C7H6Cl2N2S/c8-6-5-4(2-1-3-12-5)10-7(9)11-6/h1-3H2

Upstream product

• 58509-73-2 ethyl 3-oxothiane-2-carboxylate 
• 63449-37-6 ethyl 4-<(2-ethoxy-2-oxoethyl)sulfanyl>butanoate 
• 157414-90-9 2-(ethylthio)-7,8-dihydro-3H-thiopyrano[3,2-d]pyrimidin-4(6H)-one 
• 87466-56-6 7,8-dihydro-1H-thiopyrano[3,2-d]pyrimidine-2,4(3H,6H)-dione? 
• 38555-41-8 methyl 3-oxo-2,3,4,5-tetrahydro-6H-thiopyran-2-carboxylate 
• 38555-40-7 methyl 4-{[2-(methyloxy)-2-oxoethyl]thio}butanoate 
• 87466-55-5 7,8-dihydro-4-hydroxy-2-methylthio-6H-thiopyrano<3,2-d>pyrimidine 
• 87466-56-6 7,8-dihydro-2,4-dihydroxy-6H-thiopyrano<3,2-d>pyrimidine 

Downstream Products

• 1429638-98-1 (S)-1-cyclopropyl-3-(4-(4-(3-methylmorpholino)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-2-yl)phenyl)urea 
• 111915-16-3 7,8-dihydro-2-<4-(2-hydroxy-2-phenylethyl)piperazinyl>-4-(1-morpholinyl)-6H-thiopyrano<3,2-d>pyrimidine 
• 87466-64-6 2-(N-benzylpiperazino)-4-morpholino-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 
• 87466-51-1 2-<4-(2-chlorobenzyl)pyperazinyl>-7,8-dihydro-4-methylamino-6H-thiopyrano<3,2-d>pyrimidine 
• 87466-36-2 4-(4-Benzyl-piperazin-1-yl)-2-pyrrolidin-1-yl-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 
• 111915-05-0 2-[2-(4-Phenyl-piperazin-1-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-ylamino]-ethanol 
• 87466-66-8 4-(N-benzylpiperazino)-2-dimethylamino-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 
• 111915-15-2 2-[4-(4-Diethylamino-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-2-yl)-piperazin-1-yl]-1-phenyl-ethanol 
• 111896-64-1 4-Methoxy-2-(4-phenyl-piperazin-1-yl)-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine 
• 1552320-66-7 ethyl 2-[4-[(2-chloro-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidin-4-yl)amino]phenyl]acetate 
• 1552321-35-3 C₂₃H₂₂ClN₃O₂S 
• 1552321-34-2 C₂₃H₂₂FN₃O₂S 
• 1552321-33-1 C₂₃H₂₂FN₃O₂S 
• 1552321-13-7 C₂₃H₂₂FN₃O₂S 

Relevant academic research and scientific papers

Tetrahydrothiopyran and pyrimidine derivatives and its preparation method and application (by machine translation)

The invention discloses four diazanaphthylaone compound and its preparation method and application. The [...] and pyrimidines compound or its pharmaceutically acceptable salt or prodrug, has the following general formula I or II of the structure is shown, the invention also comprises four diazanaphthylaone compounds of preparation method and and containing one or more of such compounds in the preparation of the composition for the treatment and prevention of human immunodeficiency virus (HIV) application of the medicament. (by machine translation)

Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors

A PDE4B subtype selective inhibitor is expected to have a wider therapeutic window than non-selective PDE4 inhibitors. In this Letter, two series of 7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives and 5,5-dioxo-7,8- dihydro-6H-thiopyrano[3,2-d]pyri

MORPHOLINO SUBSTITUTED BICYCLIC PYRIMIDINE UREA OR CARBAMATE DERIVATIVES AS MTOR INHIBITORS

The invention relates to compounds of formula (I) wherein m, o, Ra, Rb, R1 and T1 have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments

Thiopyranopyrimidine compounds and acid addition salts thereof

Novel thiopyranopyrimidine compounds and the pharmaceutically acceptable acid addition salts thereof having excellent hypoglycemic activity, platelet aggregation inhibitory activity, antihistamine activity and anti-allergy activity useful for prevention and treatment of various disorders caused by diabetes, allergy and the like are disclosed.