155237-73-3Relevant academic research and scientific papers
MgBr2-promoted enantioselectIVe aryl addition of ArTi(OiPr)3 to ketones catalyzed by a titanium(IV) catalyst of N,N′-sulfonylated (1R,2R)-cyclohexane-1,2-diamine
Shu, Chao-Chi,Zhou, Shuangliu,Gau, Han-Mou
, p. 98391 - 98398 (2015/12/04)
MgBr2-promoted asymmetric addition of ArTi(OiPr)3 to ketones catalyzed by a titanium catalyst of N,N′-sulfonylated (1R,2R)-cyclohexane-1,2-diamines is reported, and results showed that the chiral N,N′-sulfonylated cyclohex
Reversal of enantioselectivity on protonation of enol(ate)s derived from 2-methyl-1-tetralone using C2-symmetric sulfonamides
Boyd, Ewan,Coumbarides, Gregory S.,Eames, Jason,Hay, Alastair,Jones, Ray V.H.,Stenson, Rachel A.,Suggate, Michael J.
, p. 9465 - 9468 (2007/10/03)
The synthesis of enantiomerically enriched (R)-2-methyl-1-tetralone 1 (64% e.e.) was achieved through protonation of its lithium enolate 3 using a C 2-symmetrical bis-sulfonamide 5d as an internal proton source. Access to the complementary (S)-enantiomer 1 (45% e.e.) can be achieved using an external quench strategy involving acetic acid as the external proton source.
Enantioselective [2,3]-wittig rearrangement via a chiral boron ester enolate
Fujimoto, Katsuhiko,Matsuhashi, Chiho,Nakai, Takeshi
, p. 423 - 435 (2007/10/02)
The first enantioselective [2,3]-Wittig rearrangement of α-(allyloxy)- acetates is described which involves a chiral boron enolate with a chiral bis-suifonamide ligand to afford the α-hydroxy-β-alkyl-γ,δ-unsaturated esters in a high enantioselectivity (>9
Catalytic enantioselective cyclopropanation with bis(halomethyl) zinc reagents. II. The effect of promoter structure on selectivity
Denmark, Scott E.,Christenson, Beritte L.,O'Connor, Stephen P.
, p. 2219 - 2222 (2007/10/02)
The catalytic, enantioselective cyclopropanation of cinnamyl alcohol has been accomplished with bis (iodomethyl)zinc in the presence of chiral bis(sulfonamides) derived from cyclohexanediamine. An extensive survey of diamine and sulfonamide structure has revealed a marked sensitivity to the spatial relationship of the amine groups, but only a modest dependence on the sulfonamide residue.
A Catalytic Enantioselective Reaction Using a C2-Symmetric Disulfonamide as a Chiral Ligand: Simmons-Smith Cyclopropanation of Allylic Alcohols by the Et2Zn-CH2I2-Disulfonamide System
Takahashi, Hideyo,Yoshioka, Masato,Shibasaki, Masakatsu,Ohno, Masaji,Imai, Nobuyuki,Kobayashi, Susumu
, p. 12013 - 12026 (2007/10/02)
A catalytic and enantioselective Simmons-Smith cyclopropanation of an allylic alcohol was developed by the reaction of an allylic alcohol with Et2Zn and CH2I2 in the presence of a catalytic amount of chiral disulfonamide 4.
