155245-89-9Relevant academic research and scientific papers
Reversal of stereoselectivity in the Evans aldol reaction of α,α-difluoro and α,α,α-trifluoro carbonyl compounds
Iseki, Katsuhiko,Oishi, Satoshi,Kobayashi, Yoshiro
, p. 71 - 84 (2007/10/02)
The Evans aldol reaction of hexafluoroacetone and trifluoroacetaldehyde causes complete reversal of diastereofacial selectivity. The boron enolate derived from N-acyloxazolidinone 2 reacts with trifluoroacetaldehyde to give anti and "non-Evans" syn aldols
Reversal of stereoselectivity in the Evans aldol reaction of α,α-difluoro and α,α,α-trifluoro carbonyl compounds
Iseki, Katsuhiko,Oishi, Satoshi,Taguchi, Takeo,Kobayashi, Yoshiro
, p. 8147 - 8150 (2007/10/02)
The Evans aldol reaction of hexafluoroacetone and trifluoroacetaldehyde causes reversal of stereoselectivity. The boron enolate derived from oxazolidinone 1 reacts with trifluoroacetaldehyde to give anti and "non-Evans" syn aldols with stereoselectivities
