155246-18-7Relevant academic research and scientific papers
Anticancer Agents, 19. Synthesis of the Reduced A-Unit (CI) of the Antitumor Antibiotic CC-1065
Tietze, Lutz F.,Grote, Thomas
, p. 2733 - 2738 (2007/10/02)
The synthesis of the reduced A-unit 2 (CI) of CC-1065 (1) using a metal-mediated cyclisation is described.Reaction of N-allyl-N-benzylaniline 4b and zirconocene(methyl) chloride with tert-BuLi leads via a zirconocene-stabilized benzyne complex 5 to the 3,
