155295-71-9

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 220589-01-5 (R)-3-Cyclopropylmethyl-5-(1-hydroxy-2-phenyl-ethyl)-dihydro-furan-2-one 
• 40734-75-6 (E)-(4-bromobut-2-en-1-yl)benzene 
• 122-78-1 phenylacetaldehyde 
• 155295-67-3 3-[(E)-2(R)-(cyclopropylmethyl)-1-oxo-6-phenyl-4-hexenyl]-4(S)-(phenylmethyl)-2-oxazolidinone 
• 155295-64-0 (E)-2(R)-(cyclopropylmethyl)-6-phenyl-4-hexenoic acid 
• 6052-66-0 1-phenyl-3-buten-2-ol 
• 155295-65-1 3-(3-cyclopropyl-1-oxopropyl)-4(S)-phenylmethyl-2-oxazolidinone 

Downstream Products

• 155417-41-7 4(R),5(S)-bis[(tert-butyldimethylsilyl)oxy]-N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-2(R)-(cyclopropylmethyl)-6-phenylhexanamide 
• 220589-04-8 (2R,4R,5S)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-cyclopropylmethyl-6-phenyl-hexanoic acid 

Relevant academic research and scientific papers

Novel small renin inhibitors containing 4,5- or 3,5-Dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2-P3 sites

Renin inhibitors containing a 4,5- or a 3,5-dihydroxy-2-substituted-6-phenylhexanamide fragment at the P2-P3 sites have been prepared and evaluated. The four possible diastereomeric diols of the two series of inhibitors were synthesi