155348-04-2Relevant academic research and scientific papers
Biotransformation of (+)- and (-)-menthol by the larvae of common cutworm (Spodoptera litura)
Miyazawa,Kumagae,Kameoka
, p. 3938 - 3940 (2007/10/03)
(+)-Menthol was mixed in an artificial diet at a concentration of 1 mg/g of diet, and the diet was fed to the last instar larvae of common cutworm (Spodoptera litura). Metabolites were recovered from grass and analyzed spectroscopically. (+)-Menthol was transformed mainly to (+)-7- hydroxymenthol. Similarly, (-)-menthol was transformed mainly to (-)-7- hydroxymenthol. The C-7 position of (+)and (-)-menthol was preferentially oxidized.
Fungal transformation of (1R,2S,5R)-(-)-menthol by Cephalosporium aphidicola
Atta-ur-Rahman,Yaqoob, Muhammad,Farooq, Afgan,Anjum, Shazia,Asif, Fahim,Choudhary, M. Iqbal
, p. 1340 - 1342 (2007/10/03)
Incubation of (1R,2S,5R)-(-)-menthol (1) with Cephalosporium aphidicola for 12 days yielded the six oxidized metabolites: 10-acetoxymenthol (2), 7- hydroxymenthol (3), 4α-hydroxymenthol (4), 3α-hydroxymenthol (5), 9- hydroxymenthol (6), and 10-hydroxymenthol (7). The structures of the novel compounds 2, 4, 5, and 7 were assigned by interpretation of their spectral data.
