155398-17-7Relevant academic research and scientific papers
Synthesis of Fungicidal (1H-1,2,4-Triazol-1-yl-methyl)silanes and -siloxanes
Liebner, Falk,Bankwitz, Uwe,Ruehlmann, Klaus
, p. 145 - 150 (2007/10/02)
The synthesis of FlusilazoleTM (1a) was substantially improved by thorough exclusion of oxygen nucleophiles in the reaction of (chloromethyl)bis(4-fluorophenyl)methylsilane with sodium 1H-1,2,4-triazolide.New α,α-diaryl-α-(1H-1,2,4-triazol-1-yl-methyl)siloxanes 3 were obtained firstly from diaryl(1H-1,2,4-triazol-1-yl-methyl)silanols or -silanolates, which were prepared by different methods from the corresponding silanol hydrochlorides and further treated with functional, linear oligodimethylsiloxanes or secondly from α,α-diaryl-α-(chloromethyl)siloxanes and 1-(trimethylsilyl)-1H-1,2,4-triazole.The siloxane 4 containing a triazolylmethyl group and additionally silicofunctional coupling groups could be synthesized by hydrosilylation of an α-triazolylmethyl-ω-vinylsiloxane with triethoxysilane. - Key Words: Fungicides / Silanes / Siloxanes / 1,2,4-Triazoles
