15540-85-9 Usage
Description
3,6-Dimethyl-2-nitroaniline is an organic compound with the molecular formula C8H10N2O2. It is characterized by the presence of two methyl groups at the 3rd and 6th positions, and a nitro group at the 2nd position of the aniline molecule. 3,6-DIMETHYL-2-NITROANILIN is known for its potential applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
3,6-Dimethyl-2-nitroaniline is used as a reagent for the preparation of quinoxaline-diones, which are potential D-amino acid oxidase inhibitors. These inhibitors play a crucial role in the development of drugs targeting various diseases, including neurodegenerative disorders and certain types of cancer. The compound's ability to form quinoxaline-diones makes it a valuable asset in the pharmaceutical industry for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 15540-85-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,5,4 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15540-85:
(7*1)+(6*5)+(5*5)+(4*4)+(3*0)+(2*8)+(1*5)=99
99 % 10 = 9
So 15540-85-9 is a valid CAS Registry Number.
15540-85-9Relevant articles and documents
Synthesis of ortho-phenylenebis(guanidine) derivatives with potential chirality
Fukuzumi, Masahiro,Nakanishi, Waka,Ishikawa, Tsutomu,Kumamoto, Takuya
, p. 1453 - 1468 (2015/02/19)
We report the synthesis and potential chirality of ortho-phenylenebisguanidines (BGs) with substituents at C(3) and C(6). Guanidinylation of 3,6-disubstituted benzene-1,2-diamines with 2-chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium chloride gave the corresponding BGs. X-Ray crystallography showed that the two guanidine moieties occupy different faces of the benzene ring, creating potential chirality, although optical resolution of tBu-substituted BG by chiral HPLC failed. However, a methylated acyclic bisguanidinium salt (BGms) was obtained as a chiral crystal with a space group of P212121.
