155412-73-0

Basic information

• Product Name: 3-DIMETHYLAMINOMETHYL-BENZOIC ACID
• Synonyms: 3-(dimethylammoniomethyl)benzoate;3-(dimethylazaniumylmethyl)benzoate;CHEMBRDG-BB 4014707;AKOS BB-9404;3-DIMETHYLAMINOMETHYL-BENZOIC ACID;TIMTEC-BB SBB010639;UKRORGSYN-BB BBV-182410;3-[(dimethylamino)methyl]benzoic acid(SALTDATA: HCl)
• CAS NO: 155412-73-0
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Mol File: 155412-73-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 290.8°C at 760 mmHg
• Flash Point: 129.7°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.000929mmHg at 25°C
• Refractive Index: 1.557
• PKA: 3.80±0.10(Predicted)
• CAS DataBase Reference: 3-DIMETHYLAMINOMETHYL-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-DIMETHYLAMINOMETHYL-BENZOIC ACID(155412-73-0)
• EPA Substance Registry System: 3-DIMETHYLAMINOMETHYL-BENZOIC ACID(155412-73-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 155412-73-0(Hazardous Substances Data)

Usage

Description

3-Dimethylaminomethyl-benzoic acid, a derivative of benzoic acid, is a chemical compound characterized by its molecular formula C10H13NO2. It features a dimethylamino group attached to the benzene ring, giving it unique properties within the realm of organic chemistry. This white crystalline solid, with a melting point of approximately 145°C, is soluble in organic solvents and is recognized for its significant role in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
3-Dimethylaminomethyl-benzoic acid serves as a crucial pharmaceutical intermediate, playing a pivotal role in the synthesis of a variety of drugs. Its chemical structure allows for versatile reactions and modifications, making it a valuable component in the development of new medicinal compounds.
Used in Controlled Release Drug Delivery Systems:
Recognizing its potential beyond traditional pharmaceutical applications, 3-Dimethylaminomethyl-benzoic acid has been studied for use in controlled release drug delivery systems. This innovative application aims to improve the efficacy and safety of drug administration by regulating the release of active pharmaceutical ingredients over time, thereby enhancing therapeutic outcomes and patient compliance.

InChI:InChI=1/C10H13NO2/c1-11(2)7-8-4-3-5-9(6-8)10(12)13/h3-6H,7H2,1-2H3,(H,12,13)

Upstream product

• 124-40-3 dimethyl amine 
• 31719-77-4 3-chloromethylbenzoic acid 
• 52178-50-4 Methyl 3-formylbenzoate 
• 89999-70-2 3-Dimethylaminomethyl-benzoic acid methyl ester 

Downstream Products

• 89999-70-2 3-Dimethylaminomethyl-benzoic acid methyl ester 
• 69383-72-8 3-(N,N-Dimethylaminomethyl)benzenemethanol 
• 1583315-29-0 C₂₇H₃₉NO₆ 
• 1583315-21-2 ((3R,4S,5S,7R,11R,12R,E)-12-ethyl-3,5,7,11-tetramethyl-2,8-dioxo-1-oxacyclododec-9-en-4-yl) 3-((dimethylamino)methyl)benzoate 
• 1383341-09-0 3-[(dimethylamino)methyl]-N-[1-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinyl]benzamide formate 
• 1357582-00-3 3-dimethylaminomethyl-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide 
• 1361414-51-8 (2-amino-4-(3-((dimethylamino)methyl)phenyl)thiazol-5-yl)(phenyl)methanone 
• 1361414-50-7 (2-(bis(4-methoxybenzyl)amino)-4-(3-((dimethylamino)methyl) phenyl) thiazol-5-yl)(phenyl)methanone 
• 1361414-49-4 N-(bis(4-methoxybenzyl)carbamothioyl)-3-((dimethylamino)methyl)benzamide 
• 901309-73-7 3-((dimethylamino)methyl)benzoyl chloride 
• 1361413-51-5 N-(5-benzoyl-4-(3-((dimethylamino)methyl)phenyl)thiazol-2-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 
• 1016195-11-1 C₂₉H₃₀FN₅O₄ 

Relevant articles and documents

IMIDAZO-CONDENSED BICYCLES AS INHIBITORS OF DISCOIDIN DOMAIN RECEPTORS (DDRS)

The invention provides a compound of formula (I) (Formula (I)) or a tautomeric form, stereochemically isomeric form, N-oxide, pharmaceutically acceptable salt or solvate thereof, wherein R2, R3, R4, Ra, Rb

NOVEL COMPOUNDS

Disclosed are retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.