155413-11-9

Upstream product

• 10432-39-0 2-(1-phenylpropylidene)malononitrile 
• 93-55-0 1-phenyl-propan-1-one 
• 2365-48-2 Methyl thioglycolate 
• 155413-19-7 2-chloro-5-methyl-4-phenylnicotinonitrile 

Downstream Products

• 582289-65-4 methyl 5-methyl-4-phenyl-3-(pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxylate 
• 1644599-65-4 methyl 3-azido-5-methyl-4-phenylthieno[2,3-b]pyridine-2-carboxylate 
• 1644599-71-2 methyl 5-methyl-4-phenyl-3-(4-propyl-1H-1,2,3-triazol-1-yl)thieno[2,3-b]pyridine-2-carboxylate 
• 1644599-77-8 methyl 5-methyl-4-phenyl-3-(4-phenyl-1H-1,2,3-triazol-1-yl)thieno[2,3-b]pyridine-2-carboxylate 
• 582289-73-4 2-azidocarbonyl-5-methyl-4-phenyl-3-(pyrrol-1-yl)thieno[2,3-b]pyridine 
• 582289-69-8 5-methyl-4-phenyl-3-(pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxylic acid 

Relevant academic research and scientific papers

Synthesis of methyl 3-azidothieno[2,3-b]pyridine-2-carboxylates and application of the huisgen reaction

The preparation of new substituted methyl 3-azidothieno[2,3-b]pyridine carboxylates by azotization of methyl 3-aminothieno[2,3-b]pyridine and subsequent treatment with sodium azide is described. Via Huisgen's 1,3-dipolar cycloaddition between substituted alkynes and the prepared azides, methyl 1,2,3-triazolo-thieno[2,3-b]pyridine carboxylates have been obtained.

SYNTHESE DE NOUVEAUX DERIVES 3-AMINO THIENO ET SELENOLOPYRIDINIQUES

Cyclisation of alkylidenemalonitriles by the Vilsmeier-Haack reagent gives 2-chloro 3-cyano pyridines.These compounds are used as starting material for the synthesis of thieno and selenolopyridines.Key words: Alkylidenemalonitriles; Vilsmeier-Haack; 2-chloro 3-cyano pyridines; thienopyridines; selenolopyridines.