15542-35-5

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Pentadienoic acid, 5-(4-bromophenyl)-, (E,E)is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4-Pentadienoic acid, 5-(4-bromophenyl)-, (E,E)is used as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties contribute to the development of effective and targeted agricultural products.
Used in Cancer Research:
2,4-Pentadienoic acid, 5-(4-bromophenyl)-, (E,E)is used as a research compound in the field of cancer research. Its potential anti-cancer properties are being studied to understand its effects on cancer cells and to explore its possible use in the development of new cancer treatments.

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 58824-56-9 1-(p-bromophenyl)prop-2-en-1-ol 
• 1300698-86-5 (E)-5-(4-bromophenyl)pent-4-enoic acid 
• 92356-71-3 (2E,4E)-5-(4-Bromo-phenyl)-penta-2,4-dienoic acid methyl ester 

Downstream Products

• 443360-63-2 (2E,4E)-5-(4-Bromo-phenyl)-penta-2,4-dienoyl chloride 
• 92356-76-8 (2E,4E)-5-(4-Bromo-phenyl)-1-piperidin-1-yl-penta-2,4-dien-1-one 
• 406725-70-0 4-[(2E)(4E)-5-(4-Bromophenyl)penta-2,4-dienoylamino]butyric acid methyl ester 

Relevant academic research and scientific papers

Unsaturated carbonyl compounds and their preparation method and application

The invention discloses a unsaturated carbonyl compounds and their preparation method and application. The unsaturated carbonyl compounds of the general formula as the molecular structure of the following formula (I) as shown: The unsaturated carbonyl com

Iridium-Catalyzed Aerobic α,β-Dehydrogenation of γ,δ-Unsaturated Amides and Acids: Activation of Both α- And β-C-H bonds through an Allyl-Iridium Intermediate

Direct aerobic α,β-dehydrogenation of γ, δ-unsaturated amides and acids using a simple iridium/copper relay catalysis system is described. We developed a new strategy that overcomes the challenging issue associated with the low α-acidity of amides and acids. Instead of α-C-H metalation, this reaction proceeds by β-C-H activation, which results in enhanced α-acidity. Conjugated dienamides and dienoic acids were synthesized in excellent yield with this reaction, which uses a simple reaction protocol. Mechanistic experiments suggest a catalyst resting state mechanism in which both α-C-H and β-C-H cleavage is accelerated.

Synthetic and spectroscopic studies of structural analogs of piper amides - The 5-aryl-2E,4E-pentadienamides

The methyl esters and piperidides of fourteen 5-aryl-2E,4E-pentadienoic acids have been synthesized starting from the corresponding aryl aldehydes.

Substituent Effects on Carbon-13 NMR Chemical Shifts of Side-chain Carbons in 5-Aryl-2E,4E-pentadienoic Acid Derivatives

The 13C NMR spectra of two series of 5-aryl-2E,4E-pentadienoic acid derivatives, viz. the methyl esters and piperidides have been determined.The chemical shifts of C-2 and C-4 show very good correlations with the Hammett ?+-constants for all the substituents investigated, except for the para-nitro group which is capable of excerting a strong -R effect.A possible explanation for this has been advanced.Hammett correlations between substituents and the chemical shifts of both C-3 and C-5 carbons using ?0 parameters are less satisfactory.A reverse chemical shift effect has been observed for these two centres.