92356-71-3

Upstream product

• 1117-71-1 methyl-4-bromo-2-butenoate 
• 623-43-8 crotonic acid methyl ester 
• 67629-62-3 methyl 4-(diethylphosphono)crotonate 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 443360-63-2 (2E,4E)-5-(4-Bromo-phenyl)-penta-2,4-dienoyl chloride 
• 92356-76-8 (2E,4E)-5-(4-Bromo-phenyl)-1-piperidin-1-yl-penta-2,4-dien-1-one 
• 15542-35-5 (2E,4E)-5-(4-bromophenyl)penta-2,4-dienoic acid 

Relevant academic research and scientific papers

Synthetic and spectroscopic studies of structural analogs of piper amides - The 5-aryl-2E,4E-pentadienamides

The methyl esters and piperidides of fourteen 5-aryl-2E,4E-pentadienoic acids have been synthesized starting from the corresponding aryl aldehydes.

Substituent Effects on Carbon-13 NMR Chemical Shifts of Side-chain Carbons in 5-Aryl-2E,4E-pentadienoic Acid Derivatives

The 13C NMR spectra of two series of 5-aryl-2E,4E-pentadienoic acid derivatives, viz. the methyl esters and piperidides have been determined.The chemical shifts of C-2 and C-4 show very good correlations with the Hammett ?+-constants for all the substituents investigated, except for the para-nitro group which is capable of excerting a strong -R effect.A possible explanation for this has been advanced.Hammett correlations between substituents and the chemical shifts of both C-3 and C-5 carbons using ?0 parameters are less satisfactory.A reverse chemical shift effect has been observed for these two centres.