155444-28-3

Basic information

• Product Name: N-(3-Bromo-2-pyridinyl)-acetamide
• Synonyms: N-(3-Bromo-2-pyridinyl)-acetamide;AcetaMide,N-(3-broMo-2-pyridinyl)-;N-(3-broMopyridin-2-yl)acetaMide
• CAS NO: 155444-28-3
• Molecular Formula: C₇H₇BrN₂O
• Molecular Weight: 215.05
• Product Categories: pharmacetical
• Mol File: 155444-28-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 365°Cat760mmHg
• Flash Point: 174.6°C
• Appearance: /
• Density: 1.63g/cm³
• Vapor Pressure: 1.62E-05mmHg at 25°C
• Refractive Index: 1.619
• PKA: 12.89±0.70(Predicted)
• CAS DataBase Reference: N-(3-Bromo-2-pyridinyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Bromo-2-pyridinyl)-acetamide(155444-28-3)
• EPA Substance Registry System: N-(3-Bromo-2-pyridinyl)-acetamide(155444-28-3)

Safety Data

• Hazardous Substances Data: 155444-28-3(Hazardous Substances Data)

Usage

General Description

N-(3-Bromo-2-pyridinyl)-acetamide, also known as 3-Bromo-2-pyridin-2-ylacetamide, is a chemical compound with the molecular formula C7H7BrN2O. It is a white to off-white crystalline powder that is soluble in organic solvents such as ethanol and methanol. N-(3-Bromo-2-pyridinyl)-acetamide is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential use as a building block in the development of novel biologically active compounds. N-(3-Bromo-2-pyridinyl)-acetamide has demonstrated antifungal and antimicrobial properties, making it a valuable component in the research and development of new drugs and treatments.

InChI:InChI=1/C7H7BrN2O/c1-5(11)10-7-6(8)3-2-4-9-7/h2-4H,1H3,(H,9,10,11)

Upstream product

• 504-29-0 2-aminopyridine 
• 5231-96-9 N-(2-pyridyl)acetamide 
• 13534-99-1 2-Amino-3-bromopyridine 
• 108-24-7 acetic anhydride 
• 626-55-1 3-Bromopyridine 
• 75-05-8 acetonitrile 

Downstream Products

• 1003961-43-0 2-{3-[acetyl-(3-bromo-pyridin-2-yl)-amino]-propenyl}-4-(tert-butyl-dimethyl-silanyloxy)-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Carboxamidation of pyridines by the system of elemental fluorine- carbonitrile-water: A useful alternative to the chichibabin amination

The title reaction with pyridine, 4-methylpyridine, 3-methylpyridine, 3- bromopyridine, nicotinonitrile, and quinoline yields 2-carboxamido derivatives regioselectively. Isoquinoline is amidated at position 1.

Synthesis and evaluation of aminopyridine derivatives as potential BACE1 inhibitors

To identify a new non-peptidyl BACE1 inhibitor, we focused on the aminopyridine structure, which binds to the active sites of BACE1. Synthesis of aminopyridine derivatives and evaluation of inhibitory activity against rBACE1 are described. The 2-aminopyri

Fused heterotricyclic compounds as inhibitors of 17beta-hydroxysteroid dehydrogenase 3

Fused heterotricyclic compounds, methods of using such compounds in the treatment of hormone sensitive diseases such as prostate cancer, and pharmaceutical compositions containing such compounds.