15547-88-3Relevant academic research and scientific papers
Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells
Young, David H.,Tice, Colin M.,Michelotti, Enrique L.,Roemmele, Renee C.,Slawecki, Richard A.,Rubio, Fernando M.,Rolling, Judith A.
, p. 1393 - 1396 (2001)
Phenylcyclohexenes (PCHs) [e.g., trans-4-nitro-5-(2,3,4-trimethoxyphenyl)cyclohexene, 2d] were found to bind weakly to the colchicine site of bovine tubulin, but are the first mimics of colchicine found to have high activity towards plant cells. Structure
