15548-39-7

Usage

Uses

Used in Pharmaceutical Applications:
2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE is used as a pharmaceutical compound for its potential antigenic effects. The expression is: 2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE is used as a pharmaceutical compound for its antigenic properties derived from Candida catenulata.
Used in Research and Development:
In the field of research and development, 2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE is used as a key component in studying the structure and function of complex carbohydrates and their interactions with biological systems. The expression is: 2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE is used as a research compound for studying carbohydrate structures and interactions.
Used in the Food Industry:
2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE may also find applications in the food industry, particularly in the development of novel food products with enhanced nutritional or functional properties. The expression is: 2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE is used as an ingredient in the food industry for developing products with improved nutritional or functional characteristics.
Used in the Chemical Industry:
In the chemical industry, 2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE can be utilized as a starting material for the synthesis of various complex carbohydrate derivatives with potential applications in different fields, such as pharmaceuticals, materials science, and biotechnology. The expression is: 2-O-ALPHA-D-MANNOPYRANOSYL-D-MANNOPYRANOSE is used as a starting material in the chemical industry for the synthesis of complex carbohydrate derivatives.

Upstream product

• 530-26-7 D-Mannose 
• 82703-50-2 benzyl 3,4,6-tri-O-benzyl-2-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside 
• 755712-80-2 guanosine diphosphate mannose 

Downstream Products

• 530-26-7 D-Mannose 

Relevant academic research and scientific papers

Large-scale preparation of the oligosaccharide phosphate fraction of Pichia holstii NRRL Y-2448 phosphomannan for use in the manufacture of PI-88

Mild acid-catalysed hydrolysis of the extracellular phosphomannan of the yeast Pichia holstii NRRL Y-2448 produces a high-molecular-weight phosphomannan core, a low-molecular-weight oligosaccharide phosphate fraction, and a neutral oligosaccharide fraction. A method was developed for the large-scale preparation of the oligosaccharide phosphate fraction, consisting predominantly of the pentasaccharide phosphate, 6-O-PO3H2-α-D-Man-(1 → 3)-α-D-man-(1 → 3)-α-D-man-(1 → 3)-α-D-man-(1 → 2)-D-man, for use in the manufacture of the promising new anti-cancer agent, PI-88. Further insights were also gained into the structure of the phosphomannan by HPLC analysis of the time course of the hydrolysis reaction.

Enzymatic synthesis of mannobioses and mannotrioses by reverse hydrolysis using α-mannosidase from Aspergillus niger

Various manno-oligosaccharides including α-D-man-(12)-D-man and α-D-man-(12)-α-D-man-(12)-D-man were formed when a highly concentrated mannose solution was incubated in the presence of α-mannosidase from Aspergillus niger. α-D-Man-(12)-D-man and α-D-man-(12)-α-D-man-(12)-D-man were isolated by activated carbon chromatography followed by high performance liquid chromatography using an amino-silica column.In addition to the above oligosaccharides, α-D-man-(13)-D-man, α-D-man-(16)-D-man, and α-D-man-(12)-α-D-man-(16)-D-man were also isolated. Keywords: Mannobioses; Mannotrioses; α-Mannosidase; Aspergillus niger

Glycosidase-catalysed synthesis of mannobioses by the reverse hydrolysis activity of α-mannosidase: Partial purification of α-mannosidases from almond meal, limpets and Aspergillus niger

Two disaccharides, α-D-Manp-(1→2)-D-Manp 6 and α-D-Manp-(1→3)-D-Manp 7, were synthesised from mannose using the reverse hydrolysis activity of the partially purified α-mannosidases from almond (Prunus amygdalus) meal and limpets (Patella vulgata). Both di

A novel two-step synthesis of α-linked mannobioses based on an acid-assisted reverse hydrolysis reaction

Instead of an enzyme-assisted reverse hydrolysis reaction for the synthesis of manno-oligosaccharides, we propose here a versatile new approach. By Fischer type glycosylation, a d-mannose solution of extremely high concentration (approximately 83% (w/w)) was incubated at 60 °C for 65 h in 0.5 M HCl. After dilution and neutralization, the small amount of formed β-linked oligosaccharides was hydrolyzed by β-mannosidase. The yields of α-d-Manp-(1→2)-d-Manp (7.9%), α-d-Manp-(1→3)-d-Manp (7.9%), and α-d-Manp-(1→6)-d-Manp (29.1%) isolated by an activated carbon column chromatography were almost identical to those of the enzymatic reaction, but the yield of α-d-Manp-(1→3)-d-Manp increased enormously by the present method.

Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N

Low-mannose (LM) structures were coupled to gold nanoparticles (Au NPs) to amplify the affinity of LMs with Cyanovirin-N (CV-N) lectins and to study the structures of CV-N variants CVNQ50C and CVNMutDB. The Royal Society of Chemistry

Synthesis and heparanase inhibitory activity of sulfated mannooligosaccharides related to the antiangiogenic agent PI-88

A stepwise synthetic route to the mannooligosaccharides from the neutral fraction of Pichia holstii phosphomannan hydrolysate, including a tetrasaccharylamine component, was developed using only two or three readily available d-mannose building blocks. Th