15548-39-7Relevant articles and documents
Large-scale preparation of the oligosaccharide phosphate fraction of Pichia holstii NRRL Y-2448 phosphomannan for use in the manufacture of PI-88
Ferro, Vito,Fewings, Kym,Palermo, Maria C.,Li, Caiping
, p. 183 - 189 (2001)
Mild acid-catalysed hydrolysis of the extracellular phosphomannan of the yeast Pichia holstii NRRL Y-2448 produces a high-molecular-weight phosphomannan core, a low-molecular-weight oligosaccharide phosphate fraction, and a neutral oligosaccharide fraction. A method was developed for the large-scale preparation of the oligosaccharide phosphate fraction, consisting predominantly of the pentasaccharide phosphate, 6-O-PO3H2-α-D-Man-(1 → 3)-α-D-man-(1 → 3)-α-D-man-(1 → 3)-α-D-man-(1 → 2)-D-man, for use in the manufacture of the promising new anti-cancer agent, PI-88. Further insights were also gained into the structure of the phosphomannan by HPLC analysis of the time course of the hydrolysis reaction.
Glycosidase-catalysed synthesis of mannobioses by the reverse hydrolysis activity of α-mannosidase: Partial purification of α-mannosidases from almond meal, limpets and Aspergillus niger
Singh, Suddham,Scigelova, Michaela,Crout, David H. G.
, p. 223 - 229 (2000)
Two disaccharides, α-D-Manp-(1→2)-D-Manp 6 and α-D-Manp-(1→3)-D-Manp 7, were synthesised from mannose using the reverse hydrolysis activity of the partially purified α-mannosidases from almond (Prunus amygdalus) meal and limpets (Patella vulgata). Both di
Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N
Wang, Xin,Matei, Elena,Deng, Lingquan,Ramstroem, Olof,Gronenborn, Angela M.,Yan, Mingdi
supporting information; experimental part, p. 8620 - 8622 (2011/09/19)
Low-mannose (LM) structures were coupled to gold nanoparticles (Au NPs) to amplify the affinity of LMs with Cyanovirin-N (CV-N) lectins and to study the structures of CV-N variants CVNQ50C and CVNMutDB. The Royal Society of Chemistry
