155535-20-9

Basic information

• Product Name: 2-Chloro-5,6,7,8-tetrahydroquinoxaline
• Synonyms: 2-Chloro-5,6,7,8-tetrahydroquinoxaline
• CAS NO: 155535-20-9
• Molecular Formula: C8H9ClN2
• Molecular Weight: 169
• Mol File: 155535-20-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 244℃
• Flash Point: 125℃
• Appearance: /
• Density: 1.252
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.07±0.20(Predicted)
• CAS DataBase Reference: 2-Chloro-5,6,7,8-tetrahydroquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5,6,7,8-tetrahydroquinoxaline(155535-20-9)
• EPA Substance Registry System: 2-Chloro-5,6,7,8-tetrahydroquinoxaline(155535-20-9)

Safety Data

• Hazardous Substances Data: 155535-20-9(Hazardous Substances Data)

Usage

General Description

2-chloro-5,6,7,8-tetrahydroquinoxaline is a chemical compound that exists as a clear, colorless to light yellow liquid. It belongs to the chemical class of quinoxalines, which are nitrogen-containing heterocyclic compounds. It has a molecular weight of 178.7 g/mol and operates under the molecular formula C8H9ClN2. 2-chloro-5,6,7,8-tetrahydroquinoxaline is less commonly known but is used in the production of other complex chemicals and as a part of some research processes. As with many chemical substances, appropriate precautions should be taken when handling it due to potential risks and reactivity.

Upstream product

• 27579-58-4 5,6,7,8-tetrahydro-2(1H)-quinoxalinone 
• 765-87-7 cyclohexane-1,2-dione 

Relevant articles and documents

RESPIRATORY SYNCYTIAL VIRUS REPLICATION INHIBITORS

The present invention concerns compounds of formula prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof wherein -a=a-a=a- represents a radical of formula -CH=CH-CH=CH-; -N=CH-CH=CH-; -CH=N-CH=CH-; -CH=CH-N=CH-; - CH=CH-CH=N-; wherein each hydrogen atom may optionally be substituted; Q is a radical of formula wherein Alk is C1-6alkanediyl; Y is a bivalent radical of formula -NR- or -CH(NRR)-; X is NR, S, S(=O), S(=O)2, O, CH2, C(=O), CH(=CH2), CH(OH), CH(CH3), CH(OCH3), CH(SCH3), CH(NRR), CH2-NR or NR-CH2; X is a direct bond, CH2, C(=O), NR, C1-4alkyl-NR, NR-C1-4alkyl; v is 2 or 3; and whereby each hydrogen in Alk and in (b-6), (b-7) and (b-8), may optionally be replaced by R; provided that when R is hydroxy or C1-6alkyloxy, then R can not replace a hydrogen atom in the alpha position relative to a nitrogen atom; G is a direct bond or optionally substituted C1-10alkanediyl; R is an optionally substituted bicyclic heterocycle; R is hydrogen, formyl, C1-6 alkylcarbonyl, Hetcarbonyl, pyrrolidinyl, piperidinyl, homopiperidinyl, C3-7cycloalkyl or C1-10alkyl substituted with N(R)2 and optionally with another substituent; R is hydrogen, hydroxy, C1-6alkyl, C1-6alkyloxy, arylC1-6alkyl or arylC1-6alkyloxy; R is hydrogen, C1-6alkyl or arylC1-6alkyl; R, R, R and R are hydrogen or C1-6alkyl; or R and R, or R and R taken together from a bivalent radical of formula -(CH2)s- wherein s is 4 or 5; R is hydrogen, C1-4alkyl, formyl, hydroxyC1-6alkyl, C1-6alkylcarbonyl or C1-6alkyloxycarbonyl; aryl is optionally substituted phenyl; Het is pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl; as respiratory syncytial virus replication inhibitors; their preparation, compositions containing them and their use as a medicine.