155589-48-3 Usage
General Description
4-CHLOROBUTYLZINC BROMIDE is a chemical compound that acts as a source of the 4-chlorobutylzinc functional group for use in organic synthesis. It is a colorless to pale yellow liquid with the chemical formula C4H8ClZnBr and a molecular weight of 233.32 g/mol. 4-CHLOROBUTYLZINC BROMIDE is commonly used in organic reactions as a mild and selective reagent for the introduction of the 4-chlorobutylzinc group, which can be further manipulated to form various functional groups. 4-CHLOROBUTYLZINC BROMIDE is a useful tool in the field of organic chemistry for the creation of complex molecules and can be used in a variety of transformations, such as cross-coupling reactions and asymmetric synthesis. Overall, this compound is an important reagent for the construction of organic molecules with potential applications in pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 155589-48-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,5,8 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 155589-48:
(8*1)+(7*5)+(6*5)+(5*5)+(4*8)+(3*9)+(2*4)+(1*8)=173
173 % 10 = 3
So 155589-48-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H8Cl.BrH.Zn/c1-2-3-4-5;;/h1-4H2;1H;/q-1;;+2/p-1/rC4H8Cl.BrZn/c1-2-3-4-5;1-2/h1-4H2;/q-1;+1
155589-48-3Relevant articles and documents
Csp3-Csp3 Bond-Forming Reductive Elimination from Well-Defined Copper(III) Complexes
Paeth, Matthew,Tyndall, Sam B.,Chen, Liang-Yu,Hong, Jia-Cheng,Carson, William P.,Liu, Xingwu,Sun, Xiaodong,Liu, Jinjia,Yang, Kundi,Hale, Elizabeth M.,Tierney, David L.,Liu, Bin,Cao, Zhi,Cheng, Mu-Jeng,Goddard, William A.,Liu, Wei
supporting information, p. 3153 - 3159 (2019/03/06)
Carbon-carbon bond-forming reductive elimination from elusive organocopper(III) complexes has been considered the key step in many copper-catalyzed and organocuprate reactions. However, organocopper(III) complexes with well-defined structures that can undergo reductive elimination are extremely rare, especially for the formation of Csp3-Csp3 bonds. We report herein a general method for the synthesis of a series of [alkyl-CuIII-(CF3)3]- complexes, the structures of which have been unequivocally characterized by NMR spectroscopy, mass spectrometry, and X-ray crystal diffraction. At elevated temperature, these complexes undergo reductive elimination following first-order kinetics, forming alkyl-CF3 products with good yields (up to 91%). Both kinetic studies and DFT calculations indicate that the reductive elimination to form Csp3-CF3 bonds proceeds through a concerted transition state, with a ΔH? = 20 kcal/mol barrier.
