155635-57-7Relevant academic research and scientific papers
Synthesis and anticancer activity of novel oxadiazole functionalized pyrazolo[3,4-b]pyridine derivatives
BHUKYA, BHADRU,GUGULOTH, HANMANTHU
, p. 1331 - 1335 (2021/06/09)
A series of novel oxadiazole functionalized pyrazolo[3,4-b]pyridine derivatives (6a-n) was synthesized using 6-thiophenyl-4- (trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-amine (1) through reaction with 2-bromoethyl acetate, followed by hydrazine hydrate
Studies on synthesis of novel pyrido[2,3-d]pyrimidine derivatives, evaluation of their antimicrobial activity and molecular docking
Veeraswamy,Madhu,Jitender Dev,Poornachandra,Shravan Kumar,Ganesh Kumar,Narsaiah
, p. 1670 - 1675 (2018/03/29)
A series of novel pyrido[2,3-d]pyrimidine derivatives 6 were prepared starting from 2-amino-3-cyano-4-trifluoromethyl-6-phenyl pyridine 3 via Grignard's reaction, cyclization followed by coupling with aliphatic and cyclic amines. All the compounds 6 were
Studies on Synthesis of Novel Pyrido[2,3-d] pyrimidine Derivatives and Their Anticancer Activity
Banda, Veeraswamy,Gaddameedi Jitender, Dev,Gautham Santhosh, Kumar,Pillalamarri Sambasiva, Rao,Chavva, Kurumurthy,Rajesh, Pamanji,Janapala Venkateswara, Rao,Banda, Narsaiah
, p. 2538 - 2544 (2018/09/25)
A series of novel pyrido[2,3-d]pyrimidine derivatives 7 were prepared starting from 2-amino nicotinonitrile 3 via Grignard?s reaction followed by cyclization and nucleophilic substitution. All the products 7 were screened against four human cancer cell li
A novel synthetic route to 2-amino-3-cyano-4-trifluoromethyl-6-substituted pyridines
Narsaiah, B.,Sivaprasad, A.,Venkataratnam, R. V.
, p. 87 - 90 (2007/10/02)
2-Amino-3-cyano-4-trifluoromethyl-6-substituted pyridines have been obtained from 3-cyano-4-trifluoromethyl-6-substituted-2(1H)pyridones via an interesting rearrangement of 2-O-acetamido-3-cyano-4-trifluoromethyl-6-substituted pyridine intermediates.
