155639-31-9

Basic information

• Product Name: N-(4-methoxybenzyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]amine
• Synonyms: N-(4-methoxybenzyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]amine
• CAS NO: 155639-31-9
• Molecular Formula: C19H22N2O2
• Molecular Weight: 310.4
• Mol File: 155639-31-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-methoxybenzyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxybenzyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]amine(155639-31-9)
• EPA Substance Registry System: N-(4-methoxybenzyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]amine(155639-31-9)

Safety Data

• Hazardous Substances Data: 155639-31-9(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 

Relevant articles and documents

Influence of amine substituents on 5-HT2A versus 5-HT2C binding of phenylalkyl- and indolylalkylamines

The effect of 15 different amine substituents on 5-HT2A and 5-HT2C serotonin receptor binding was investigated for two series of compounds (i.e., phenylalkylamine and indolylalkylamine derivatives). In general, amine substitution decreases receptor affinity; however, N-(4-bromobenzyl) substitution results in compounds that bind at 5-HT2A receptors with high affinity (K(i) 100-fold selectivity. Although parallel structural modifications in the two series result in parallel shifts in 5- HT2C binding, these same modifications alter 5-HT2A binding in a less consistent manner.