155650-93-4Relevant academic research and scientific papers
Unexpected Reaction of Dipeptidyl Chloromethyl Ketone during Acid Hydrolysis
Taguchi, Hiroaki,Yokoi, Toshio,Kasuya, Fumiyo,Nishiyama, Yasuhiro,Fukui, Miyoshi,Okada, Yoshio
, p. 247 - 248 (1994)
Amino acid recovery of dipeptidyl chloromethyl ketones is remarkably low owing to the formation of 2-hydroxy-3,6-dialkyl-5-methylpyrazine during acid hydrolysis.
Amino acids and peptides. XL. Synthesis of Ac-Tyr-Val-Ala-Asp-MCA using newly developed acetylating reagent
Taguchi,Hirano,Yokoi,Asada,Okada
, p. 1336 - 1339 (2007/10/02)
2-Acetoxy-3-benzyl-5-methyl-6-isobutylpyrazine was prepared by cyclization of H-Phe-Leu-CH2Cl, followed by acetylation with acetic anhydride. This pyrazine derivative can react with amino groups of amino acids or peptides to produce acetyl amin
Amino acids and peptides. XLI. Facile synthesis of 5-methyl-2(1H)-pyrazinone derivatives from dipeptidyl chloromethyl ketones
Taguchi,Yokoi,Tsukatani,Okada
, p. 7361 - 7372 (2007/10/02)
5-Methyl-2(1H)-pyrazinone derivatives were easily synthesized by short reflux of dipeptidyl chloromethyl ketone hydrochlorides in MeOH.
