155653-63-7Relevant academic research and scientific papers
THE N-BOC GROUP AS AN ACTIVATOR FOR THE α-LITHIATION OF CARBAMATES: SYNTHESIS OF 11-SUBSTITUTED DIBENZOXAZEPINES
Hagen, Timothy J.,Rafferty, Michael F.,Collins, Joe T.,Garland, Danny J.,Li, James J.,et al.
, p. 601 - 612 (2007/10/02)
A series of 11-substituted dibenzoxazepines was prepared via α-lithiation utilizing the N-Boc group as an activator.The N-Boc group directs metalation of 5 by n-BuLi to the benzylic C-11 carbon.For 6 which contains 1,3 interrelated directed metalation gro
