15568-58-8Relevant academic research and scientific papers
Structural studies on bioactive compounds. 28. Selective activity of triazenyl-substituted pyrimethamine derivatives against Pneumocystis carinii dihydrofolate reductase
Stevens, Malcolm F. G.,Phillip, Keith S.,Rathbone, Daniel L.,O'Shea, Dennis M.,Queener, Sherry F.,Schwalbe, Carl H.,Lambert, Peter A.
, p. 1886 - 1893 (1997)
Triazenyl-substituted pyrimethamine derivatives 10a-s have been prepared by coupling diazotized 2,4-diamino-5-(3-amino-4-chlorophenyl)-6-ethyl pyrimidine (1c) with a series of secondary amines in aqueous sodium carbonate solution. The triazenes which are
